Next Article in Journal
Investigation on the Effect of Dose, Frequency and Duration of Allergen Exposure on Development of Staphylococcal Infections in a Chronic Model of Canine Atopic Dermatitis
Next Article in Special Issue
Application of Hyperbaric Oxygen Therapy (HBOT) as a Healing Aid after Extraction of Incisors in the Equine Odontoclastic Tooth Resorption and Hypercementosis Syndrome
Previous Article in Journal
MyD88 Mediates Colitis- and RANKL-Induced Microfold Cell Differentiation
Previous Article in Special Issue
Assessment of Changes in the Oral Microbiome That Occur in Dogs with Periodontal Disease
Article

Effectiveness of a Nanohydroxyapatite-Based Hydrogel on Alveolar Bone Regeneration in Post-Extraction Sockets of Dogs with Naturally Occurring Periodontitis

1
Master’s Degree Program in Veterinary Science, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand
2
Small Animal Hospital, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50200, Thailand
3
Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand
4
Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand
5
Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand
6
Department of Veterinary Bioscience and Veterinary Public Health, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand
7
Department of Companion Animals and Wildlife Clinic, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand
8
Integrative Research Center for Veterinary Circulatory Sciences, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand
*
Author to whom correspondence should be addressed.
Academic Editors: João Filipe Martins Freire Requicha, Carlos Alberto Antunes Viegas and Fidel San Román Ascaso
Vet. Sci. 2022, 9(1), 7; https://doi.org/10.3390/vetsci9010007
Received: 24 November 2021 / Revised: 12 December 2021 / Accepted: 15 December 2021 / Published: 26 December 2021
(This article belongs to the Special Issue New insights on Veterinary Dentistry and Oral Surgery)
Pathological mandibular fracture after dental extraction usually occurs in dogs with moderate to severe periodontitis. A nanohydroxyapatite-based hydrogel (HAP hydrogel) was developed to diminish the limitations of hydroxyapatite for post-extraction socket preservation (PSP). However, the effect of the HAP hydrogel in dogs has still not been widely investigated. Moreover, there are few studies on PSP in dogs suffering from clinical periodontitis. The purpose of this study was to evaluate the effectiveness of the HAP hydrogel for PSP in dogs with periodontitis. In five dogs with periodontitis, the first molar (309 and 409) of each hemimandible was extracted. Consequently, all the ten sockets were filled with HAP-hydrogel. Intraoral radiography was performed on the day of operation and 2, 4, 8 and 12 weeks post operation. The Kruskal–Wallis test and paired t-test were adopted for alveolar bone regeneration analysis. The results demonstrated that the radiographic grading, bone height measurement, and bone regeneration analysis were positively significant at all follow-up times compared to the day of operation. Moreover, the scanning electron microscopy with energy-dispersive X-ray spectroscopy imaging after immersion showed a homogeneous distribution of apatite formation on the hydrogel surface. Our investigation suggested that the HAP hydrogel effectively enhances socket regeneration in dogs with periodontitis and can be applied as a bone substitute for PSP in veterinary dentistry. View Full-Text
Keywords: veterinary dentistry; veterinary periodontology; nanohydroxyapatite; hydrogel; alveolar bone regeneration; periodontitis; dogs veterinary dentistry; veterinary periodontology; nanohydroxyapatite; hydrogel; alveolar bone regeneration; periodontitis; dogs
Show Figures

Figure 1

MDPI and ACS Style

Tanongpitchayes, K.; Randorn, C.; Lamkhao, S.; Chokethawai, K.; Rujijanagul, G.; Na Lampang, K.; Somrup, L.; Boonyapakorn, C.; Thongkorn, K. Effectiveness of a Nanohydroxyapatite-Based Hydrogel on Alveolar Bone Regeneration in Post-Extraction Sockets of Dogs with Naturally Occurring Periodontitis. Vet. Sci. 2022, 9, 7. https://doi.org/10.3390/vetsci9010007

AMA Style

Tanongpitchayes K, Randorn C, Lamkhao S, Chokethawai K, Rujijanagul G, Na Lampang K, Somrup L, Boonyapakorn C, Thongkorn K. Effectiveness of a Nanohydroxyapatite-Based Hydrogel on Alveolar Bone Regeneration in Post-Extraction Sockets of Dogs with Naturally Occurring Periodontitis. Veterinary Sciences. 2022; 9(1):7. https://doi.org/10.3390/vetsci9010007

Chicago/Turabian Style

Tanongpitchayes, Kittidaj, Chamnan Randorn, Suphatchaya Lamkhao, Komsanti Chokethawai, Gobwute Rujijanagul, Kannika Na Lampang, Luddawon Somrup, Chavalit Boonyapakorn, and Kriangkrai Thongkorn. 2022. "Effectiveness of a Nanohydroxyapatite-Based Hydrogel on Alveolar Bone Regeneration in Post-Extraction Sockets of Dogs with Naturally Occurring Periodontitis" Veterinary Sciences 9, no. 1: 7. https://doi.org/10.3390/vetsci9010007

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop