Red-Skin Extracts of Lotus Seeds Alleviate High-Fat-Diet Induced Obesity via Regulating Lipoprotein Lipase Activity
1
China-Canada Joint Laboratory of Food Nutrition and Health (Beijing), Beijing Engineering and Technology Research Center of Food Additives, School of Food and Health, Beijing Technology & Business University (BTBU), Beijing 100048, China
2
Beijing Academy of Food Sciences, Beijing 100068, China
*
Author to whom correspondence should be addressed.
Academic Editor: Kazuo Miyashita
Foods 2022, 11(14), 2085; https://doi.org/10.3390/foods11142085
Received: 23 June 2022
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Revised: 8 July 2022
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Accepted: 11 July 2022
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Published: 13 July 2022
(This article belongs to the Special Issue Intervention Effect of Natural Food Products on Chronic Diseases)
In recent years, obesity has become an epidemic and an important public health concern. This study was designed to explore the anti-obesity effects of red-skin extracts (RSE) from lotus seeds on high-fat-diet (HFD)-fed mice. In this study, a total of 55 phenolic compounds from the RSE were tentatively characterized using a UPLC-Q/TOF-MS system, including 9 phenolic acids and derivatives, 40 flavonoids, 2 proanthocyanidin, and 4 coumarins and derivatives. Our data demonstrated that RSE could significantly ameliorate obesity characteristics of HFD-fed mice by regulating tissue specific lipoprotein lipase (LPL) activities. In detailed, the activity and expression of LPL in adipose tissue was inhibited, and the activity and expression of LPL in skeletal muscle tissue was enhanced. Overall, these findings suggested that RSE from the red skin of lotus seeds could serve as a great candidate for a value-added, functional ingredient due to its anti-obesity effects via the regulation of LPL activity.
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Keywords:
lotus; polyphenols; obesity; lipoprotein lipase
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MDPI and ACS Style
Xu, H.; Gao, H.; Liu, F.; Gong, L. Red-Skin Extracts of Lotus Seeds Alleviate High-Fat-Diet Induced Obesity via Regulating Lipoprotein Lipase Activity. Foods 2022, 11, 2085. https://doi.org/10.3390/foods11142085
AMA Style
Xu H, Gao H, Liu F, Gong L. Red-Skin Extracts of Lotus Seeds Alleviate High-Fat-Diet Induced Obesity via Regulating Lipoprotein Lipase Activity. Foods. 2022; 11(14):2085. https://doi.org/10.3390/foods11142085
Chicago/Turabian StyleXu, Hong, Hang Gao, Feiyue Liu, and Lingxiao Gong. 2022. "Red-Skin Extracts of Lotus Seeds Alleviate High-Fat-Diet Induced Obesity via Regulating Lipoprotein Lipase Activity" Foods 11, no. 14: 2085. https://doi.org/10.3390/foods11142085
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