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Separations, Volume 8, Issue 2

2021 February - 13 articles

Cover Story: In the environment, pharmaceutical residues are a research field of particular interest due to the adverse effects on either human health or aquatic and soil environment. Analytical chemistry plays an essential part in this research, providing high-quality information by applying two different approaches: (i) target analysis and (ii) screening methods for the determination of non-target or unknown compounds (degradation products). This overview illustrated the procedures most applied in sample preparation, chromatographic, and detection methods to meet the requirements and demands of environmental water analysis by pinpointing their advantages and drawbacks. The main issues of the validation procedure were also addressed. View this paper.
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Articles (13)

  • Article
  • Open Access
14 Citations
3,669 Views
11 Pages

(1) Background: ZIF-67 is one of the most intriguing metal–organic frameworks already applied in liquid adsorption. To increase its adsorption performance, dual ionic liquids were immobilized on ZIF-67 in this research; (2) Methods: The obtained sorb...

  • Article
  • Open Access
2 Citations
4,231 Views
11 Pages

Adenine nucleotides—adenosine monophosphate, diphosphate, and triphosphate—are of utmost importance to all living organisms, where they play a critical role in the energy metabolism and are tied to allosteric regulation in various regulatory enzymes....

  • Article
  • Open Access
12 Citations
6,736 Views
20 Pages

ESI–LC–MS/MS for Therapeutic Drug Monitoring of Binary Mixture of Pregabalin and Tramadol: Human Plasma and Urine Applications

  • Atiah H. Almalki,
  • Nesma A. Ali,
  • Fadwa A. Elroby,
  • Mohamed R. El Ghobashy,
  • Aml A. Emam and
  • Ibrahim A. Naguib

Tramadol (TRM) and pregabalin (PGB) are frequently used in combination for neuropathic pain management. Accordingly, a selective and sensitive high-performance liquid chromatography–electrospray ionization–mass/mass spectrometric (ESI–LC–MS/MS) metho...

  • Article
  • Open Access
18 Citations
6,324 Views
26 Pages

In the last few years, the flavored beer market has increased significantly. In particular, consumers showed a growing interest in citrus-flavored beers. Citrus fruits contain, among other class of compounds, terpenes and terpenoids and oxygenated he...

  • Article
  • Open Access
3 Citations
3,192 Views
11 Pages

Natural products with antimycobacterial adjuvant potential may be utilized to address the rise of multidrug-resistant tuberculosis (TB). The antioxidant-rich oil palm (Elaeis guineensis) fruit (OPF) was investigated for antimycobacterial activity aga...

  • Review
  • Open Access
43 Citations
13,274 Views
50 Pages

In the environment, pharmaceutical residues are a field of particular interest due to the adverse effects to either human health or aquatic and soil environment. Because of the diversity of these compounds, at least 3000 substances were identified an...

  • Feature Paper
  • Article
  • Open Access
9 Citations
4,421 Views
12 Pages

Purified extracts from different types of berries and medicinal plants are increasingly used as raw materials for the production of nutraceuticals and dietary supplements, mainly due to their high content in bioactive substances. This is, for instanc...

  • Article
  • Open Access
7 Citations
10,086 Views
19 Pages

The association between humans and cats (Felis catus) is well known. This domestic animal is also known for its malodorous urine and feces. The complexity of the odorous urine and feces impacts human life by triggering the human sensory organ in a ne...

  • Feature Paper
  • Article
  • Open Access
20 Citations
5,840 Views
22 Pages

Multi-Target Analysis and Suspect Screening of Xenobiotics in Milk by UHPLC-HRMS/MS

  • Mikel Musatadi,
  • Belén González-Gaya,
  • Mireia Irazola,
  • Ailette Prieto,
  • Nestor Etxebarria,
  • Maitane Olivares and
  • Olatz Zuloaga

The development of suspect or non-target screening methods to detect xenobiotics in biological fluids is essential to properly understand the exposome and assess its adverse health effects on humans. In order to fulfil that aim, the biomonitorization...

  • Article
  • Open Access
4 Citations
6,951 Views
12 Pages

A solid-phase extraction (SPE) procedure was developed for simultaneous monitoring of sixteen different phenolics of various polarity, quantified by high-performance liquid chromatography (HPLC). The procedure allowed screening the accumulation of in...

  • Article
  • Open Access
5 Citations
3,345 Views
8 Pages

Phytochemical and Biological Traits of Endemic Betonica bulgarica (Lamiaceae)

  • Tsvetelina Mladenova,
  • Plamen Stoyanov,
  • Krasimir Todorov,
  • Delyana Davcheva,
  • Gergana Kirova,
  • Tanya Deneva,
  • Donika Gyuzeleva,
  • Rumen Mladenov and
  • Anelia Bivolarska

Betonica bulgarica is an endemic species distributed in Bulgaria. The chemical composition of the essential oil analysed by GC–MS (Gas chromatography–mass spectrometry) and the content of trace elements analysed by ICP–MS (Inductive...

  • Article
  • Open Access
19 Citations
11,894 Views
10 Pages

An HPLC-DAD Method to Quantify Flavonoids in Sonchus arvensis and Able to Classify the Plant Parts and Their Geographical Area through Principal Component Analysis

  • Rifki Husnul Khuluk,
  • Amalia Yunita,
  • Eti Rohaeti,
  • Utami Dyah Syafitri,
  • Roza Linda,
  • Lee Wah Lim,
  • Toyohide Takeuchi and
  • Mohamad Rafi

A simple and efficient method has been developed for the simultaneous determination of eight flavonoids (orientin, hyperoside, rutin, myricetin, luteolin, quercetin, kaempferol, and apigenin) in Sonchus arvensis by high-performance liquid chromatogra...

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Separations - ISSN 2297-8739