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Open AccessCase Report

Pancreatitis in A Patient with Cystic Fibrosis Taking Ivacaftor

1
Cystic fibrosis Department, Agia Sophia Children’s Hospital, 115 27 Athens, Greece
2
Division of Pediatric Pulmonology, First Department of Pediatrics, National and Kapodistrian University of Athens School of Medicine and Aghia Sophia Children’s Hospital, 115 27 Athens, Greece
*
Author to whom correspondence should be addressed.
Children 2020, 7(1), 6; https://doi.org/10.3390/children7010006
Received: 26 November 2019 / Revised: 18 December 2019 / Accepted: 20 December 2019 / Published: 12 January 2020
Pancreatitis is rare in pancreatic insufficient cystic fibrosis patients. While pancreatic insufficiency has been considered irreversible until now, in the current era of new therapies with modulators of the Cystic Fibrosis Transmembrane Regulator CFTR channel, there are reports of improvement of pancreatic exocrine function. We describe the case of an adolescent with cystic fibrosis who developed pancreatitis after the partial recovery of pancreatic function while taking ivacaftor. This case adds to the limited body of evidence that CFTR modulators lead to the improvement of pancreatic exocrine function in cystic fibrosis. View Full-Text
Keywords: pancreatitis; cystic fibrosis; ivacaftor; CFTR pancreatitis; cystic fibrosis; ivacaftor; CFTR
MDPI and ACS Style

Petrocheilou, A.; Kaditis, A.G.; Loukou, I. Pancreatitis in A Patient with Cystic Fibrosis Taking Ivacaftor. Children 2020, 7, 6.

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