Abstract
Background/Objectives: Sensory processing constitutes a fundamental neurobiological mechanism that allows individuals to perceive, interpret, and respond adaptively to sensory input. Atypical patterns of sensory processing are frequently observed in neurodevelopmental disorders such as Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD). The purpose of this study was to evaluate the psychometric properties of the Greek Sensory Profile 2 Short Form following its linguistic and cross-cultural adaptation. Methods: An on-site parent-report survey was conducted among children and adolescents aged 3.0 to 14.11 years across Greece. The study included the Sensory Profile 2 Short Form (SSP2), the Child Behavior Checklist (CBCL), and the Social Communication Questionnaire (SCQ). A total of 350 parents participated in the study. Results: The present study demonstrated that the Greek version of the SSP2 possesses good psychometric properties. The results of the Exploratory Factor Analysis (EFA) of the 34 items explained 63.6% of the total variance. Internal consistency for both primary scales—Sensory (α = 0.93) and Behavioral (α = 0.96)—was satisfactory, as were the subscales Seeking (α = 0.88), Avoiding (α = 0.94), Sensitivity (α = 0.94), and Registration (α = 0.91). Significant correlations with the CBCL and SCQ supported convergent validity. The findings also highlighted associations with sociodemographic variables, providing insights into population-specific variations in sensory processing. Conclusions: The Greek version of the SSP2 demonstrates strong psychometric properties and is suitable for assessing sensory processing patterns in children and adolescents. Its use enables culturally appropriate screening for atypical sensory processing, informing both research and clinical practice and supporting early identification and intervention strategies.