Abstract
Due to the facts that epidemic-related parameters vary significantly in different stages of infectious diseases and are relatively stable within the same stage, infectious disease models should be switch-type models. However, research on switch-type infectious disease models is scarce due to the complexity and intricate design of switching rules. This scarcity has motivated the writing of this paper. By assuming that switching instants and impulse times occur at different moments, this paper proposes switch rules suitable for impulse control and derives synchronization criteria for reaction–diffusion switch-type infectious disease systems under impulse control. The effectiveness of this method is validated through numerical simulations. It is important to mention that, based on the information available to us, this paper is currently the sole study focusing on switch-type reaction–diffusion models for infectious diseases.
Keywords:
reaction–diffusion; Lyapunov–Krasovskii functional; switched epidemic systems; impulsive control MSC:
34K24; 34K45
1. Introduction
As is well known, infectious diseases exhibit significant diffusion effects, and, thus, reaction–diffusion epidemic models have been recently studied in the literature. Stability analysis and synchronization control of infectious disease models have theoretical implications in practical epidemic management [1,2]. For instance, in reference [3], the author explored the stability of the wavefront in a delayed monostable reaction–diffusion epidemic system. The motivation behind the extensive focus on the dynamical stability of infectious disease models is rooted in the inherent difficulty of completely eliminating such diseases. Achieving stability in the interaction between susceptible and infected populations is a crucial objective in the realm of infectious disease prevention and control [3,4,5,6,7,8,9,10]. Reference [4], for example, conducted research on susceptible–infected–recovered dynamics, taking into account the impact of the healthcare system. Their study considered a general incidence rate function and recovery rate dependent on the number of hospital beds, establishing the existence, uniqueness, and boundedness of the model. It extensively investigated all possible steady-state solutions and their stability. In another case, reference [5] explored an epidemic model incorporating an incubation period, newborns, and vaccination for susceptible individuals. Their study demonstrated global stability through Lyapunov functions. Reference [6] derived stability conditions for an infectious disease model with delays by constructing appropriate Lyapunov functionals. Reference [7] delved into an SIR epidemic model with nonlinear incidence and delay, discussing the local stability of equilibrium states, both disease-free and endemic, through the analysis of the corresponding characteristic equation. Moreover, synchronization control of infectious disease models holds theoretical significance in practical epidemic management [1,2,11,12,13,14,15]. Reference [11] highlighted long-term spatiotemporal disease occurrence data indicating synchronization in many frequently occurring epidemics, especially childhood infections, between suburbs. The authors employed modeling techniques to elucidate the existence of synchronization phenomena. Reference [12] proposed a synchronization-based method for identifying parameters and estimating latent variables from real data in epidemic models. An adaptive synchronization method, based on an observer approach, was suggested, utilizing effective guiding parameters derived solely from real data. To validate identifiability and estimation results, a numerical simulation of a tuberculosis model was conducted using actual data from the central region of Cameroon. This study demonstrated that certain tools of nonlinear system synchronization can aid in addressing parameter and state estimation problems in the field of epidemiology. Reference [13] investigated synchronization between two identical susceptible–infected–recovered chaotic systems with fractional-order time derivatives.
The inclusion of a specific incubation period in infectious diseases necessitates the incorporation of models with delayed feedback in the mathematical modeling of these diseases. However, research in this field is very rare, which has motivated the writing of this article. Additionally, infectious diseases exhibit significant differences at different stages, and switch systems provide a good representation of infectious disease models. However, switch-type infectious disease models are seldom studied, providing another motivation for this article. Therefore, this article aims to investigate reaction–diffusion delayed feedback epidemic systems and intends to achieve synchronous control of infectious disease switch models through the use of pulse control techniques.
This article introduces innovations in three aspects:
- ♢
- For the first time, this article introduces synchronous control of switch-type infectious disease models.
- ♢
- For the first time, this article develops switching rules for infectious disease models.
- ♢
- For the first time, this article successfully derives global exponential synchronization criteria specifically for impulse reaction–diffusion infectious disease models.
2. System Description
Recently, reaction–diffusion epidemic models have been studied in the literature. For instance, in the year 2020, reference [1] considered a reaction–diffusion epidemic model. In the year 2022, the authors of reference [2] investigated a delayed impulse reaction–diffusion epidemic model.
where , and the function is the fraction of the susceptible population, is the infected fraction, is the recovered fraction, and for In addition,
Moreover, the disease transmission rate is denoted by , and the recovery rate is denoted by . Taking into account the practical situation of delayed feedback in epidemic models, this paper considers the following delayed feedback epidemic model:
where is a family of positive definite diagonal matrices, which represents the delayed feedback parameters under the switching mode . Here, . represents the moments of pulses, satisfying with Assume that ,
Here, and are positive scalars for , and is the diffusion coefficient matrix.
System (3) is the drive system, and its response system can be considered as follows:
Then, the error system is proposed as follows:
where , is the time delay with and
Additionally, , and f are defined in (4).
Obviously, .
Definition 1.
If the error system (6) is globally exponentially stable with a convergence rate of , then we say that system (5) globally exponentially synchronizes to system (3) with a synchronization rate of .
Definition 2.
To establish the switching rule :
() Choose the initial mode , if .
() For each if and keep . On the other hand, if but , i.e., hitting a switching surface, choose the next mode by applying (8) and begin to switch.
Here, we assume that the switching moment and the impulse moment do not occur simultaneously and
and
where is a scalar, E is an identity matrix, P is an undetermined positive definite symmetric matrix, and is the smallest positive eigenvalue of the following eigenvalue problem:
Remark 1.
Firstly, from Figure 1, we can see that the pulse moment and the switching moment do not occur simultaneously. That is, the state transition curve does not exhibit a pulse burst shape. The dynamic indications caused by the pulse only show significant changes around the switching points. Secondly, the idea of state-dependent switching can be briefly described in Figure 1. The solutions initiate from different initial points within mode 1 (). Subsequently, upon reaching the boundary of mode 1, where it intersects exclusively with mode 2 (), the system transitions to mode 2, as illustrated by the blue curve in Figure 1. Similarly, when reaching the boundary of mode 1 that intersects exclusively with mode 3 (), the system switches to mode 3, represented by the red curve in Figure 1. Lastly, upon reaching the boundary of mode 1, which intersects with both mode 2 and mode 3, the system undergoes a switch to the mode determined by the minimum of law (8), as depicted by the black curve in Figure 1.
Figure 1.
Switching behavior under impulse.
Lemma 1
([16]). Let , , and . Then, we have
Lemma 2
([17]). Suppose and several positive scalars , and , satisfying:
(i) , for any and ;
(ii) , , , whenever for , where is a scalar;
(iii) , where are scalars;
(iv) and .
Then, the null solution of the delayed differential equation with impulse
is globally exponentially stable with a convergent rate for any time delays .
3. Main Results
Theorem 1.
System (5) globally exponentially asymptotically synchronizes with system (3), and its synchronization rate is , if the following conditions (a)–(c) are satisfied:
(a) There is a scalar such that
(b) There exist scalars and such that
and
(c) There exist scalars with such that
Proof.
Consider the following Lyapunov–Krasovskii functional,
Let , where P is a positive definite symmetric matrix. Then, there are such that
which satisfies condition (i) of Lemma 2.
Due to , and (7), we can see this by using the differential along the trajectory of system (6) that
If there exists such that , by (15), we can obtain that
Next, we will derive the following inequlity based on the switching rule from (16).
Firstly, we claim that
Indeed, since there exist scalars with such that Hence, utilizing proof by contradiction, it is not difficult to deduce the validity of Equation (18). With the establishment of Equation (18), we can now prove the validity of (17).
In fact, according to the switching law , when and we can obtain, by the definition of , that
Note that the above expression also holds when . Therefore, overall, we only need to consider the case where .
When and this means that the trajectory hits a switching surface. Due to (18), the minimum law (8) deduces that there must exist a such that and
To this end, we obtain if , i.e.,
In other words, condition (ii) of Lemma 2 is satisfied.
Additionally,
which implies that condition (iii) of Lemma 2 holds.
Furthermore, based on the conditions of Theorem 1, condition (iv) of Lemma 2 is satisfied.
Therefore, according to Lemma 2, error system (6) is globally exponentially stable with a convergence rate of In other words, system (5) is globally exponentially synchronized with system (3), and its synchronization rate is □
Remark 2.
Theorem 1 ingeniously addresses the challenges of synchronizing control that arise from the interplay of reaction–diffusion processes, time delays, and impulsive control. Specifically, it overcomes the mathematical difficulties induced by the diffusion term by employing Poincare inequalities, designs an appropriate Lyapunov function, sets suitable pulse intervals and pulse intensities, and, ultimately, achieves synchronization control through the utilization of the delayed-impulse inequalities lemma.
Remark 3.
The switching rule of Theorem 1 is different from the switching rule in reference [18]. Meanwhile, synchronization control results for epidemic models have been achieved using impulse control. This is the first time that synchronization control has been obtained for a reaction–diffusion epidemic model under a switching rule.
Discussion 1.
In epidemic prevention and control, the impulse moment is artificially determined and may not coincide with the switching moment. Therefore, this paper assumes that the impulse moment and switching moment do not occur simultaneously, which is reasonable. However, if one were to consider their simultaneous occurrence, the design of switching rules in this paper would need further consideration and discussion. This poses an interesting question worth exploring in more depth.
Discussion 2.
Stochastic perturbations and stochastic models are widely employed in various fields, including infectious disease models ([6,19,20]). Exploring how to control the dynamics of infectious diseases through impulse control under stochastic perturbations is an intriguing question.
4. Numerical Example
Now, we verify the effectiveness of Theorem 1 via the following numerical example.
Example 1.
Let . Then, ([21], Remark 14). In addition, set and Then, Let and
Set , Then,
Let
Then
Let . Then we obtain
and
Finally, let with . We can see it that
Thus far, all conditions of Theorem 1 have been satisfied. Therefore, according to Theorem 1, error system (6) is globally exponentially stable with a convergence rate of . In other words, system (5) is globally exponentially asymptotically synchronized with system (3), and its synchronization rate is (see Figure 2, Figure 3 and Figure 4).
Figure 2.
Numerical result of in (3) and in (5).
Figure 3.
Numerical result of in (3) and in (5).
Figure 4.
Numerical result of in (3) and in (5).
Remark 4.
Numerical simulation results indicate that, despite the relatively small impulse strength, significant effectiveness in synchronizing control of the epidemic model can be achieved as long as an appropriate pulse interval is set. This validates the effectiveness of Theorem 1.
Example 2.
In Example 1, let
Then
Let , and other data of Example 1 hold unchanged. Then, we obtain and
and
Finally, let with . We can see it that
Thus far, all conditions of Theorem 1 have been satisfied. Therefore, according to Theorem 1, error system (6) is globally exponentially stable with a convergence rate of . In other words, system (5) is globally exponentially asymptotically synchronized with system (3), and its synchronization rate is (see Figure 5, Figure 6 and Figure 7).
Figure 5.
Numerical result of in (3) and in (5).
Figure 6.
Numerical result of in (3) and in (5).
Figure 7.
Numerical result of in (3) and in (5).
Remark 5.
The numerical results indicate that, despite the enlargement of the impulse interval, as the impulse intensity increases, the convergence speed of synchronization still remains, which can be listed as Table 1:
Table 1.
Comparisons of Example 1 and Example 2.
5. Conclusions
Synchronized control flow epidemic models have significant theoretical guidance, especially when there are substantial differences in the development stages of the epidemic. For instance, in the recent COVID-19 pandemic, various parameters, such as the number of infections and susceptible individuals, differ significantly across stages. The truth is that parameters related to different stages have notable distinctions. Impulse control, in essence, involves the momentary input intensity of artificial prevention measures and drug deployment treatment in different stages. Synchronized control under impulse measures allows for the gradual synchronization of heavily affected areas, where artificial measures are input in batches, in response to the evolving and fluctuating nature of the epidemic. This helps reduce the severity of the epidemic in heavily affected areas and gradually synchronize them with regions where the situation is improving. The synchronized control epidemic model offers significant theoretical guidance, especially when there are substantial differences in the development stages of the epidemic. Therefore, this paper considers a switching-type epidemic model. By establishing appropriate switching rules and utilizing impulse control techniques, global exponential synchronization criteria are obtained. Numerical examples demonstrate the effectiveness of the proposed methods. It is worth noting that this paper improves upon some existing methods in the literature and applies them for the first time to epidemic models, providing insights for a future series of related improvements.
Author Contributions
Conceptualization, R.R. and Q.Z.; methodology, R.R.; software, R.R.; validation, R.R. and Q.Z.; formal analysis, R.R. and Q.Z.; investigation, R.R.; resources, R.R.; data curation, R.R.; writing—original draft preparation, R.R.; writing—review and editing, R.R.; visualization, R.R.; supervision, Q.Z.; project administration, Q.Z.; funding acquisition, Q.Z. All authors have read and agreed to the published version of the manuscript.
Funding
This research was funded by the Applied Basic Research Project of the Sichuan Provincial Department of Science and Technology (2020YJ0434).
Institutional Review Board Statement
Not applicable.
Informed Consent Statement
Not applicable.
Data Availability Statement
Data sharing is not applicable to this article.
Conflicts of Interest
The authors declare no conflict of interest.
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