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Proteomes, Volume 1, Issue 2

September 2013 - 7 articles

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Articles (7)

  • Review
  • Open Access
3 Citations
6,904 Views
21 Pages

High-Throughput Proteomic Approaches to the Elucidation of Potential Biomarkers of Chronic Allograft Injury (CAI)

  • Hilary Cassidy,
  • Jennifer Slyne,
  • Helena Frain,
  • Craig Slattery,
  • Michael P. Ryan and
  • Tara McMorrow

23 September 2013

This review focuses on the role of OMICs technologies, concentrating in particular on proteomics, in biomarker discovery in chronic allograft injury (CAI). CAI is the second most prevalent cause of allograft dysfunction and loss in the first decade...

  • Article
  • Open Access
42 Citations
11,849 Views
31 Pages

Quantitative Analysis of the Human Milk Whey Proteome Reveals Developing Milk and Mammary-Gland Functions across the First Year of Lactation

  • Qiang Zhang,
  • Judy K. Cundiff,
  • Sarah D. Maria,
  • Robert J. McMahon,
  • Jessica G. Woo,
  • Barbara S. Davidson and
  • Ardythe L. Morrow

3 September 2013

In-depth understanding of the changing functions of human milk (HM) proteins and the corresponding physiological adaptions of the lactating mammary gland has been inhibited by incomplete knowledge of the HM proteome. We analyzed the HM whey proteome...

  • Review
  • Open Access
18 Citations
9,472 Views
19 Pages

27 August 2013

Identification of biomarkers capable of differentiating between pathophysiological states of an individual is a laudable goal in the field of proteomics. Protein biomarker discovery generally employs high throughput sample characterization by mass sp...

  • Review
  • Open Access
49 Citations
15,845 Views
22 Pages

Exosomal Proteome Profiling: A Potential Multi-Marker Cellular Phenotyping Tool to Characterize Hypoxia-Induced Radiation Resistance in Breast Cancer

  • Stefani N. Thomas,
  • Zhongping Liao,
  • David Clark,
  • Yangyi Chen,
  • Ramin Samadani,
  • Li Mao,
  • David K. Ann,
  • Janet E. Baulch,
  • Paul Shapiro and
  • Austin J. Yang

9 August 2013

Radiation and drug resistance are significant challenges in the treatment of locally advanced, recurrent and metastatic breast cancer that contribute to mortality. Clinically, radiotherapy requires oxygen to generate cytotoxic free radicals that caus...

  • Review
  • Open Access
25 Citations
10,052 Views
17 Pages

Impact of Solar Radiation on Gene Expression in Bacteria

  • Sabine Matallana-Surget and
  • Ruddy Wattiez

16 July 2013

Microorganisms often regulate their gene expression at the level of transcription and/or translation in response to solar radiation. In this review, we present the use of both transcriptomics and proteomics to advance knowledge in the field of bacter...

  • Article
  • Open Access
21 Citations
8,467 Views
30 Pages

Serum Proteome Analysis for Profiling Predictive Protein Markers Associated with the Severity of Skin Lesions Induced by Ionizing Radiation

  • Thibault Chaze,
  • Louis Hornez,
  • Christophe Chambon,
  • Iman Haddad,
  • Joelle Vinh,
  • Jean-Philippe Peyrat,
  • Marc Benderitter and
  • Olivier Guipaud

10 July 2013

The finding of new diagnostic and prognostic markers of local radiation injury, and particularly of the cutaneous radiation syndrome, is crucial for its medical management, in the case of both accidental exposure and radiotherapy side effects. Especi...

  • Article
  • Open Access
46 Citations
8,153 Views
15 Pages

Effect of External Electric Field Stress on Gliadin Protein Conformation

  • Ashutosh Singh,
  • Shirin Munshi and
  • Vijaya Raghavan

A molecular dynamic (MD) modeling approach was applied to evaluate the effect of external electric field on gliadin protein structure and surface properties. Static electric field strengths of 0.001 V/nm and 0.002 V/nm induced conformational changes...

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Proteomes - ISSN 2227-7382