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Plants 2018, 7(4), 87;

The CLV-WUS Stem Cell Signaling Pathway: A Roadmap to Crop Yield Optimization

Plant Gene Expression Center, United States Department of Agriculture-Agricultural Research Service, Albany, CA 94710, USA
Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
Received: 12 September 2018 / Revised: 9 October 2018 / Accepted: 10 October 2018 / Published: 19 October 2018
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The shoot apical meristem at the growing shoot tip acts a stem cell reservoir that provides cells to generate the entire above-ground architecture of higher plants. Many agronomic plant yield traits such as tiller number, flower number, fruit number, and kernel row number are therefore defined by the activity of the shoot apical meristem and its derivatives, the floral meristems. Studies in the model plant Arabidopsis thaliana demonstrated that a molecular negative feedback loop called the CLAVATA (CLV)-WUSCHEL (WUS) pathway regulates stem cell maintenance in shoot and floral meristems. CLV-WUS pathway components are associated with quantitative trait loci (QTL) for yield traits in crop plants such as oilseed, tomato, rice, and maize, and may have played a role in crop domestication. The conservation of these pathway components across the plant kingdom provides an opportunity to use cutting edge techniques such as genome editing to enhance yield traits in a wide variety of agricultural plant species. View Full-Text
Keywords: CLE; CLV; WUS; stem cells; meristem; SAM; signaling; locule CLE; CLV; WUS; stem cells; meristem; SAM; signaling; locule

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Fletcher, J.C. The CLV-WUS Stem Cell Signaling Pathway: A Roadmap to Crop Yield Optimization. Plants 2018, 7, 87.

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