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Plants 2018, 7(3), 67;

Chiricaspi (Brunfelsia grandiflora, Solanaceae), a Pharmacologically Promising Plant

Centro de Investigación Biomédica, Facultad de Ciencias de la Salud Eugenio Espejo, Universidad Tecnológica Equinoccial, Av. Mariscal Sucre y Mariana de Jesús, Quito 170527, Ecuador
Department of Vegetal Biology, Ecology and Earth Science, Faculty of Sciences, University of Extremadura, 06071 Badajoz, Spain
Herbario Alfredo Paredes, QAP, Universidad Central de Ecuador, Quito 170129, Ecuador
Author to whom correspondence should be addressed.
Received: 28 June 2018 / Revised: 6 August 2018 / Accepted: 13 August 2018 / Published: 18 August 2018
(This article belongs to the Special Issue Medicinal Plants and Natural Product Research)
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This study’s objective was to evaluate the rescued traditional knowledge about the chiricaspi (Brunfelsia grandiflora s.l.), obtained in an isolated Canelo-Kichwa Amazonian community in the Pastaza province (Ecuador). This approach demonstrates well the value of biodiversity conservation in an endangered ecoregion. The authors describe the ancestral practices that remain in force today. They validated them through bibliographic revisions in data megabases, which presented activity and chemical components. The authors also propose possible routes for the development of new bioproducts based on the plant. In silico research about new drug design based on traditional knowledge about this species can produce significant progress in specific areas of childbirth, anesthesiology, and neurology. View Full-Text
Keywords: activity; bioproduct; Brunfelsia; Amazonian; Ecuador; ethnobotanic; ayahuasca; validation; drug discovery; scopoletin activity; bioproduct; Brunfelsia; Amazonian; Ecuador; ethnobotanic; ayahuasca; validation; drug discovery; scopoletin

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Luzuriaga-Quichimbo, C.X.; Hernández del Barco, M.; Blanco-Salas, J.; Cerón-Martínez, C.E.; Ruiz-Téllez, T. Chiricaspi (Brunfelsia grandiflora, Solanaceae), a Pharmacologically Promising Plant. Plants 2018, 7, 67.

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