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Journal of Developmental Biology, Volume 11, Issue 2

June 2023 - 14 articles

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Articles (14)

  • Article
  • Open Access
5 Citations
3,408 Views
21 Pages

Regionalized Protein Localization Domains in the Zebrafish Hair Cell Kinocilium

  • Timothy Erickson,
  • William Paul Biggers,
  • Kevin Williams,
  • Shyanne E. Butland and
  • Alexandra Venuto

Sensory hair cells are the receptors for auditory, vestibular, and lateral line sensory organs in vertebrates. These cells are distinguished by “hair”-like projections from their apical surface collectively known as the hair bundle. Along...

  • Feature Paper
  • Review
  • Open Access
12 Citations
6,425 Views
22 Pages

The Lost and Found: Unraveling the Functions of Orphan Genes

  • Ali Zeeshan Fakhar,
  • Jinbao Liu,
  • Karolina M. Pajerowska-Mukhtar and
  • M. Shahid Mukhtar

Orphan Genes (OGs) are a mysterious class of genes that have recently gained significant attention. Despite lacking a clear evolutionary history, they are found in nearly all living organisms, from bacteria to humans, and they play important roles in...

  • Feature Paper
  • Review
  • Open Access
4,526 Views
22 Pages

Whole genome duplication (WGD) or polyploidization can occur at the cellular, tissue, and organismal levels. At the cellular level, tetraploidization has been proposed as a driver of aneuploidy and genome instability and correlates strongly with canc...

  • Feature Paper
  • Article
  • Open Access
1 Citations
2,859 Views
22 Pages

The mouth is a central feature of our face, without which we could not eat, breathe, or communicate. A critical and early event in mouth formation is the creation of a “hole” which connects the digestive system and the external environmen...

  • Article
  • Open Access
2,991 Views
18 Pages

Transcription of HOX Genes Is Significantly Increased during Neuronal Differentiation of iPSCs Derived from Patients with Parkinson’s Disease

  • Viya B. Fedoseyeva,
  • Ekaterina V. Novosadova,
  • Valentina V. Nenasheva,
  • Lyudmila V. Novosadova,
  • Igor A. Grivennikov and
  • Vyacheslav Z. Tarantul

Parkinson’s disease (PD) is the most serious movement disorder, but the actual cause of this disease is still unknown. Induced pluripotent stem cell-derived neural cultures from PD patients carry the potential for experimental modeling of under...

  • Feature Paper
  • Article
  • Open Access
6 Citations
2,726 Views
15 Pages

Osteoderm Development during the Regeneration Process in Eurylepis taeniolata Blyth, 1854 (Scincidae, Sauria, Squamata)

  • Gennady O. Cherepanov,
  • Dmitry A. Gordeev,
  • Daniel A. Melnikov and
  • Natalia B. Ananjeva

Osteoderms are bony structures that develop within the dermal layer of the skin in vertebrates and are very often found in different lizard families. Lizard osteoderms are diverse in topography, morphology, and microstructure. Of particular interest...

  • Feature Paper
  • Review
  • Open Access
3 Citations
3,749 Views
19 Pages

Primary oocyte determination occurs in many organisms within a germ line cyst, a multicellular structure composed of interconnected germ cells. However, the structure of the cyst is itself highly diverse, which raises intriguing questions about the b...

  • Feature Paper
  • Article
  • Open Access
6 Citations
3,905 Views
23 Pages

Attenuation of Dopaminergic Neurodegeneration in a C. elegans Parkinson’s Model through Regulation of Xanthine Dehydrogenase (XDH-1) Expression by the RNA Editase, ADR-2

  • Lindsey A. Starr,
  • Luke E. McKay,
  • Kylie N. Peter,
  • Lena M. Seyfarth,
  • Laura A. Berkowitz,
  • Kim A. Caldwell and
  • Guy A. Caldwell

Differential RNA editing by adenosine deaminases that act on RNA (ADARs) has been implicated in several neurological disorders, including Parkinson’s disease (PD). Here, we report results of a RNAi screen of genes differentially regulated in ad...

  • Article
  • Open Access
1 Citations
2,720 Views
14 Pages

The Presence of Two MyoD Genes in a Subset of Acanthopterygii Fish Is Associated with a Polyserine Insert in MyoD1

  • Lewis J. White,
  • Alexander J. Russell,
  • Alastair R. Pizzey,
  • Kanchon K. Dasmahapatra and
  • Mary E. Pownall

28 April 2023

The MyoD gene was duplicated during the teleost whole genome duplication and, while a second MyoD gene (MyoD2) was subsequently lost from the genomes of some lineages (including zebrafish), many fish lineages (including Alcolapia species) have retain...

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