Next Article in Journal
An Efficient, Robust, and Inexpensive Grinding Device for Herbal Samples like Cinchona Bark
Previous Article in Journal
A Rapid, Cost-Effective Pre-Clinical Method to Screen for Pro- or Antiarrhythmic Effects of Substances in an Isolated Heart Preparation
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Sci. Pharm.
Volume 83
Issue 2
10.3797/scipharm.1410-10
scipharm-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Screening of Panamanian Plant Extracts for Pesticidal Properties and HPLC-Based Identification of Active Compounds

by
Niels GULDBRANDSEN
1,
Maria DE MIERI
1,
Mahabir GUPTA
2,
Tobias SEISER
3,
Christine WIEBE
3,
Joachim DICKHAUT
3,
Rüdiger REINGRUBER
3,
Oliver SORGENFREI
3 and
Matthias HAMBURGER
1,*
1
Division of Pharmaceutical Biology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, CH-4056 Basel, Switzerland.
2
CIFLORPAN, College of Pharmacy, University of Panama, Apartado 0824-00172, Panama, Republic of Panama.
3
BASF SE, Carl-Bosch-Strasse 38, D-67056 Ludwigshafen, Germany.
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2015, 83(2), 353-367; https://doi.org/10.3797/scipharm.1410-10
Submission received: 17 October 2014 / Accepted: 11 December 2014 / Published: 11 December 2014
Versions Notes

Abstract

A library of 600 taxonomically diverse Panamanian plant extracts was screened for fungicidal, insecticidal, and herbicidal activities. A total of 19 active extracts were submitted to HPLC-based activity profiling, and extracts of Bocconia frutescens, Miconia affinis, Myrcia splendens, Combretum aff. laxum, and Erythroxylum macrophyllum were selected for the isolation of compounds. Chelerythrine (2), macarpine (3), dihydrosanguinarine (5), and arjunolic acid (8) showed moderate-to-good fungicidal activity. Myricetin-3-O-(6''-O-galloyl)-β-galactopyranoside (13) showed moderate insecticidal activity, but no compound with herbicidal activity was identified.
Keywords: Panamanian plant extracts; HPLC-based activity profiling; Fungicide; Insecticide; Herbicide Panamanian plant extracts; HPLC-based activity profiling; Fungicide; Insecticide; Herbicide

Share and Cite

MDPI and ACS Style

GULDBRANDSEN, N.; DE MIERI, M.; GUPTA, M.; SEISER, T.; WIEBE, C.; DICKHAUT, J.; REINGRUBER, R.; SORGENFREI, O.; HAMBURGER, M. Screening of Panamanian Plant Extracts for Pesticidal Properties and HPLC-Based Identification of Active Compounds. Sci. Pharm. 2015, 83, 353-367. https://doi.org/10.3797/scipharm.1410-10

AMA Style

GULDBRANDSEN N, DE MIERI M, GUPTA M, SEISER T, WIEBE C, DICKHAUT J, REINGRUBER R, SORGENFREI O, HAMBURGER M. Screening of Panamanian Plant Extracts for Pesticidal Properties and HPLC-Based Identification of Active Compounds. Scientia Pharmaceutica. 2015; 83(2):353-367. https://doi.org/10.3797/scipharm.1410-10

Chicago/Turabian Style

GULDBRANDSEN, Niels, Maria DE MIERI, Mahabir GUPTA, Tobias SEISER, Christine WIEBE, Joachim DICKHAUT, Rüdiger REINGRUBER, Oliver SORGENFREI, and Matthias HAMBURGER. 2015. "Screening of Panamanian Plant Extracts for Pesticidal Properties and HPLC-Based Identification of Active Compounds" Scientia Pharmaceutica 83, no. 2: 353-367. https://doi.org/10.3797/scipharm.1410-10

APA Style

GULDBRANDSEN, N., DE MIERI, M., GUPTA, M., SEISER, T., WIEBE, C., DICKHAUT, J., REINGRUBER, R., SORGENFREI, O., & HAMBURGER, M. (2015). Screening of Panamanian Plant Extracts for Pesticidal Properties and HPLC-Based Identification of Active Compounds. Scientia Pharmaceutica, 83(2), 353-367. https://doi.org/10.3797/scipharm.1410-10

Article Metrics

Back to TopTop