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Scientia Pharmaceutica, Volume 78, Issue 1

2010 March - 12 articles

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Articles (12)

  • Article
  • Open Access
187 Citations
8,310 Views
13 Pages

13 February 2010

Forty four extracts from sixteen plants used traditionally as anticancer agents were evaluated in vitro for their antiproliferative activity against Hep-2, MCF-7, and Vero cell lines. Plants were fractionated using ethanol, methanol, chloroform, n-he...

  • Article
  • Open Access
15 Citations
1,737 Views
13 Pages

18 January 2010

The aim of present investigation was 1) to evaluate the in vivo bioavailability of an Etodolac (ETD)-β-cyclodextrin (β-CD) inclusion complex system prepared by kneading and spray drying techniques in rats, 2) to study the pharmacodynamic parameters i...

  • Editorial
  • Open Access
1,407 Views
14 Pages

18 January 2010

Die Zeitschrift Scientia Pharmaceutica (www.scipharm.at) erscheint vierteljährlich jeweils am Quartalsende und ist ein Medium zur Publikation von Originalarbeiten, Kurzmitteilungen und ausgewählten Übersichtsarbeiten aus allen wissenschaftlichen Disz...

  • Article
  • Open Access
13 Citations
1,483 Views
8 Pages

29 December 2009

Spontaneous neoplasm metastasis, a fatalist pathological feature of cancer, is a long-evolving, multi-steps process that can now only be treated or controlled by drugs or immuno-modulators. As we have previously hypothesized, each drug or immuno-modu...

  • Article
  • Open Access
35 Citations
2,766 Views
14 Pages

19 December 2009

Microspheres (MS) of Ketorolac Tromethamine (KT) for oral delivery were prepared by complex coacervation (method-1) and simple coacervation (method-2) methods without the use of chemical cross–linking agent (glutaraldehyde) to avoid the toxic reactio...

  • Article
  • Open Access
48 Citations
4,790 Views
9 Pages

19 December 2009

The present study was oriented towards microencapsulation of aspirin and the study of its release kinetics. The desired encapsulation was achieved by emulsion solvent evaporation method using ethyl cellulose (EC), cellulose acetate phthalate (CAP) an...

  • Article
  • Open Access
17 Citations
1,722 Views
12 Pages

11 December 2009

(9-Methyl-5,6-dihydronaphtho[1',2':4,5]thieno[2,3-d]pyrimidin-11-yl)hydrazine (1) was used as a precursor for preparation of some novel 1-(9-methyl-5,6- dihydronaphtho[1',2':4,5]thieno[2,3-d]pyrimidin-11-yl)-1H-pyrazoles 27, -1H-isoindole- 1,3(2H)-d...

  • Article
  • Open Access
74 Citations
2,997 Views
11 Pages

6 December 2009

The alkaloidal fraction (AFCP) of roots of Cissampelos pareira Linn. was screened for in-vitro antioxidant activity and immunomodulatory activity in mice. The HPTLC finger print profile was also established for the identification of AFCP which was fo...

  • Article
  • Open Access
48 Citations
2,140 Views
22 Pages

3 December 2009

The present study was aimed at evaluating the possible use of inter polymer complexed (IPC) films of chitosan (CH) and carboxymethyl tamarind kernel powder (CMTKP) for colon release of budesonide. Viscosity analysis of the supernatant liquid obtained...

  • Article
  • Open Access
37 Citations
2,434 Views
10 Pages

Preparation and In Vivo Evaluation of Indomethacin Loaded True Nanoemulsions

  • Faiyaz SHAKEEL,
  • Wafa RAMADAN,
  • Huda M. GARGUM and
  • Rajinder SINGH

23 November 2009

Indomethacin, a potent nonsteroidal anti-inflammatory drug, has been used in the treatment of various kinds of pains, inflammation and arthritis. However, oral administration of indomethacin produces serious gastrointestinal adverse effects. Therefor...

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Sci. Pharm. - ISSN 2218-0532