- Editorial
Editorial
- Wolfgang KUBELKA
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2008 March - 8 articles
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Abstract Structural similarity is one of the basic underlying principles in drug discovery and development. Numerous algorithms and concepts are known to search compound libraries for analogous compounds assuming that similar compounds show similar b...
The title compound (2) was prepared by reaction of 4-chlorocinnoline with glycidol/sodium hydride in dry DMF, since treatment of cinnolin-4-ol with epichlorohydrin as well as oxidation of 4-allyloxycinnoline did not succeed. Reaction of 2 with primar...
Sensitive methods were developed for the determination of two sulfhydrylcontaining drugs namely acetylcysteine (I) and captopril (II). The methods were based on reacting the drugs with 4-chloro-7-nitro-2,1,3-benzoxadiazole (NBD-Cl) in the presence of...
The principles of Traditional Mongolian Medicine (TMM) and a short history of this medical tradition as practised in the Republic of Mongolia are provided. TMM represents an Asian medical tradition which is greatly influenced by Tibetan Buddhism and...
In the last years intoxications after consumption of Illicium verum Hook. f. have been reported due to adulterations with I. anisatum L.. Many efforts have already been made to develop a simple method which would enable the detection of I. anisatum i...
Many bead biopharmaceutical characteristics are dependent on the bead shape. Furthermore, the shape is one of crucial parameters for incorporation of beads in more complex drug delivery system. Therefore, the aim of this study was to evaluate the inf...
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