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Use of Population-Based Health Informatics Research to Improve Care for Patients with Cardiovascular Diseases

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Division of Molecular & Clinical Medicine, School of Medicine, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, UK
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Health Informatics Centre, Ninewells Hospital & Medical School, Dundee DD1 9SY, UK
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Author to whom correspondence should be addressed.
Diseases 2020, 8(4), 47; https://doi.org/10.3390/diseases8040047
Received: 16 November 2020 / Revised: 14 December 2020 / Accepted: 15 December 2020 / Published: 17 December 2020
There are common clinical scenarios in chronic heart disease where no randomized controlled data exist to guide management, and it is likely that well-designed observational studies will have to be used to inform clinical practice. Showing the clinical applicability of this type of study design, using record linkage of population electronic health records, we have provided key observational evidence that use of renin–angiotensin-system (RAS) blockers is associated with better outcomes in patients with aortic stenosis and that metformin could be used safely as an antiglycemic drug in patients with diabetes and heart failure. Each of these pieces of underpinning research has made a major contribution to relevant international clinical practice guidelines, helped the Food and Drug Administration in their decision making and changed prescribing practice. View Full-Text
Keywords: population electronic health records; renin–angiotensin system blockers; aortic stenosis; metformin; heart failure population electronic health records; renin–angiotensin system blockers; aortic stenosis; metformin; heart failure
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MDPI and ACS Style

Mordi, I.R.; Guignard-Duff, M.; Hall, C.; New, B.J.M.; Lang, C.C. Use of Population-Based Health Informatics Research to Improve Care for Patients with Cardiovascular Diseases. Diseases 2020, 8, 47. https://doi.org/10.3390/diseases8040047

AMA Style

Mordi IR, Guignard-Duff M, Hall C, New BJM, Lang CC. Use of Population-Based Health Informatics Research to Improve Care for Patients with Cardiovascular Diseases. Diseases. 2020; 8(4):47. https://doi.org/10.3390/diseases8040047

Chicago/Turabian Style

Mordi, Ify R., Magalie Guignard-Duff, Christopher Hall, Benjamin J.M. New, and Chim C. Lang 2020. "Use of Population-Based Health Informatics Research to Improve Care for Patients with Cardiovascular Diseases" Diseases 8, no. 4: 47. https://doi.org/10.3390/diseases8040047

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