Diseases, Volume 12, Issue 1
January 2024 - 29 articles
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Cover Story: Acute pancreatitis is increasingly frequent, and inflammation plays a crucial role. Fifty acute pancreatitis patients and a healthy control of fifteen individuals had peripheral blood samples analyzed for B and T cell subpopulations at the time of hospitalization and 48 h after diagnosis. The percentages of B cells and the percentages of the CD27-IgD- B cell subset decreased from admission to 48 h after admission. The patients with higher BISAP scores showed lower percentages of peripheral lymphocytes but higher percentages of CD27-IgD- B cells. Higher BISAP, neutrophil/lymphocyte ratios, and peripheral blood B cell levels emerged as predictors of hospital stay length. Additionally, the neutrophil/lymphocyte ratio along with the BISAP score and circulating B cell levels form a robust predictive model for hospital stay duration. View this paper