Next Article in Journal
Spatial and Temperature Resolutions of Magnetic Nanoparticle Temperature Imaging with a Scanning Magnetic Particle Spectrometer
Next Article in Special Issue
Active Food Packaging Coatings Based on Hybrid Electrospun Gliadin Nanofibers Containing Ferulic Acid/Hydroxypropyl-Beta-Cyclodextrin Inclusion Complexes
Previous Article in Journal
Investigation of the Microstructures of Graphene Quantum Dots (GQDs) by Surface-Enhanced Raman Spectroscopy
Previous Article in Special Issue
Recent Developments in Food Packaging Based on Nanomaterials
Article Menu
Issue 10 (October) cover image

Export Article

Open AccessArticle
Nanomaterials 2018, 8(10), 865;

Anchoring Gated Mesoporous Silica Particles to Ethylene Vinyl Alcohol Films for Smart Packaging Applications

Instituto de Agroquímica y Tecnología de Alimentos, IATA-CSIC, Grupo de Envases, Av. Agustin Escardino 7, 46980 Paterna, Spain
Departamento de Tecnología de Alimentos, Grupo de Investigación e Innovación Alimentaria, Universitat Politècnica de València. Camino de Vera s/n, 46022 Valencia, Spain
Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València. Departamento de Química, Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, Spain
CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Camino de Vera s/n, 46022 Valencia, Spain
Author to whom correspondence should be addressed.
Received: 2 October 2018 / Revised: 19 October 2018 / Accepted: 20 October 2018 / Published: 22 October 2018
(This article belongs to the Special Issue Food Packaging Based on Nanomaterials)
PDF [3779 KB, uploaded 22 October 2018]


This work is a proof of concept for the design of active packaging materials based on the anchorage of gated mesoporous silica particles with a pH triggering mechanism to a packaging film surface. Mesoporous silica micro- and nanoparticles were loaded with rhodamine B and functionalized with N-(3-trimethoxysilylpropyl)diethylenetriamine. This simple system allows regulation of cargo delivery as a function of the pH of the environment. In parallel, poly(ethylene-co-vinyl alcohol) films, EVOH 32 and EVOH 44, were ultraviolet (UV) irradiated to convert hydroxyl moieties of the polymer chains into –COOH functional groups. The highest COOH surface concentration was obtained for EVOH 32 after 15 min of UV irradiation. Anchoring of the gated mesoporous particles to the films was carried out successfully at pH 3 and pH 5. Mesoporous particles were distributed homogeneously throughout the film surface and in greater concentration for the EVOH 32 films. Films with the anchored particles were exposed to two liquid media simulating acidic food and neutral food. The films released the cargo at neutral pH but kept the dye locked at acidic pH. The best results were obtained for EVOH 32 irradiated for 15 min, treated for particle attachment at pH 3, and with mesoporous silica nanoparticles. This opens the possibility of designing active materials loaded with antimicrobials, antioxidants, or aromatic compounds, which are released when the pH of the product approaches neutrality, as occurs, for instance, with the release of biogenic amines from fresh food products. View Full-Text
Keywords: MCM-41; gated mesoporous silica particles; EVOH films; anchorage on film surface; active packaging; pH-mediated delivery MCM-41; gated mesoporous silica particles; EVOH films; anchorage on film surface; active packaging; pH-mediated delivery

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
Printed Edition Available!
A printed edition of this Special Issue is available here.

Share & Cite This Article

MDPI and ACS Style

Muriel-Galet, V.; Pérez-Esteve, É.; Ruiz-Rico, M.; Martínez-Máñez, R.; Barat, J.M.; Hernández-Muñoz, P.; Gavara, R. Anchoring Gated Mesoporous Silica Particles to Ethylene Vinyl Alcohol Films for Smart Packaging Applications. Nanomaterials 2018, 8, 865.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Nanomaterials EISSN 2079-4991 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top