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Cyclodextrin-Based Functional Glyconanomaterials
 
 
Review

Glyconanomaterials for Human Virus Detection and Inhibition

1
Department of Biocatalysis, Institute of Catalysis (CSIC), Marie Curie 2, 28049 Madrid, Spain
2
Department of Chemistry, Maynooth University, Maynooth, W23VP22 County Kildare, Ireland
*
Author to whom correspondence should be addressed.
Academic Editors: John H.T. Luong and Hicham Fenniri
Nanomaterials 2021, 11(7), 1684; https://doi.org/10.3390/nano11071684
Received: 6 May 2021 / Revised: 21 June 2021 / Accepted: 23 June 2021 / Published: 26 June 2021
(This article belongs to the Special Issue Functional Glyconanomaterials)
Viruses are among the most infectious pathogens, responsible for the highest death toll around the world. Lack of effective clinical drugs for most viral diseases emphasizes the need for speedy and accurate diagnosis at early stages of infection to prevent rapid spread of the pathogens. Glycans are important molecules which are involved in different biological recognition processes, especially in the spread of infection by mediating virus interaction with endothelial cells. Thus, novel strategies based on nanotechnology have been developed for identifying and inhibiting viruses in a fast, selective, and precise way. The nanosized nature of nanomaterials and their exclusive optical, electronic, magnetic, and mechanical features can improve patient care through using sensors with minimal invasiveness and extreme sensitivity. This review provides an overview of the latest advances of functionalized glyconanomaterials, for rapid and selective biosensing detection of molecules as biomarkers or specific glycoproteins and as novel promising antiviral agents for different kinds of serious viruses, such as the Dengue virus, Ebola virus, influenza virus, human immunodeficiency virus (HIV), influenza virus, Zika virus, or coronavirus SARS-CoV-2 (COVID-19). View Full-Text
Keywords: glycan; nanomaterial; glycoconjugates; nanoparticles; virus; coronavirus; SARS-CoV-2; biosensor; antiviral drug glycan; nanomaterial; glycoconjugates; nanoparticles; virus; coronavirus; SARS-CoV-2; biosensor; antiviral drug
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MDPI and ACS Style

Losada-Garcia, N.; Garcia-Sanz, C.; Andreu, A.; Velasco-Torrijos, T.; Palomo, J.M. Glyconanomaterials for Human Virus Detection and Inhibition. Nanomaterials 2021, 11, 1684. https://doi.org/10.3390/nano11071684

AMA Style

Losada-Garcia N, Garcia-Sanz C, Andreu A, Velasco-Torrijos T, Palomo JM. Glyconanomaterials for Human Virus Detection and Inhibition. Nanomaterials. 2021; 11(7):1684. https://doi.org/10.3390/nano11071684

Chicago/Turabian Style

Losada-Garcia, Noelia, Carla Garcia-Sanz, Alicia Andreu, Trinidad Velasco-Torrijos, and Jose M. Palomo. 2021. "Glyconanomaterials for Human Virus Detection and Inhibition" Nanomaterials 11, no. 7: 1684. https://doi.org/10.3390/nano11071684

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