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Journal of Functional Biomaterials, Volume 14, Issue 11

November 2023 - 22 articles

Cover Story: AMPs are a promising bioactive class of molecules. The review highlights how the incorporation of AMPs into medical implants and biomaterials has exhibited remarkable potential in mitigating biofilm formation and preventing infections. Cutting-edge advancements in biomedical sciences take center stage, revealing the successful immobilization of AMPs to enhance their efficacy and stability within the implant environment. The narrative unfolds with a spotlight on the latest research, where AMP coatings have proven effective in treating surgical site infections (SSIs), dental applications, enhancing contact lenses, fortifying bone grafts, and combating urinary tract infections (UTIs). Each instance underscores the versatility and adaptability of AMPs in diverse clinical settings. View this paper
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Articles (22)

  • Review
  • Open Access
7 Citations
7,856 Views
24 Pages

10 November 2023

Coronary artery disease is the most prevalent cardiovascular disease, claiming millions of lives annually around the world. The current treatment includes surgically inserting a tubular construct, called a stent, inside arteries to restore blood flow...

  • Review
  • Open Access
3 Citations
3,531 Views
21 Pages

Recent Progress of In Vitro 3D Culture of Male Germ Stem Cells

  • Jiang Wu,
  • Kai Kang,
  • Siqi Liu,
  • Yaodan Ma,
  • Meng Yu and
  • Xin Zhao

8 November 2023

Male germline stem cells (mGSCs), also known as spermatogonial stem cells (SSCs), are the fundamental seed cells of male animal reproductive physiology. However, environmental influences, drugs, and harmful substances often pose challenges to SSCs, s...

  • Article
  • Open Access
4 Citations
4,007 Views
18 Pages

Assessment of the Penetration of an Endodontic Sealer into Dentinal Tubules with Three Different Compaction Techniques Using Confocal Laser Scanning Microscopy

  • Ignacio Barbero-Navarro,
  • Diego Velázquez-González,
  • María Esther Irigoyen-Camacho,
  • Marco Antonio Zepeda-Zepeda,
  • Paulo Mauricio,
  • David Ribas-Perez and
  • Antonio Castano-Seiquer

7 November 2023

Adequate root canal sealing is essential for the success of endodontic treatment. There are numerous techniques available; identifying simple and efficient techniques is important to provide good patient care. The purpose of the study was to compare...

  • Article
  • Open Access
9 Citations
3,501 Views
16 Pages

A pH-Responsive DNA Tetrahedron/Methotrexate Drug Delivery System Used for Rheumatoid Arthritis Treatment

  • Yi Jin,
  • Xingyu Ge,
  • Yinjin Xu,
  • Siyi Wang,
  • Qian Lu,
  • Aidong Deng,
  • Jingjing Li and
  • Zhifeng Gu

3 November 2023

Rheumatoid arthritis (RA) is a chronic autoimmune disorder that leads to progressive and aggressive joint inflammation. The disease process is characterized by the activation of macrophages, which then release tumor necrosis factor-α (TNF-&alph...

  • Article
  • Open Access
15 Citations
4,624 Views
17 Pages

2 November 2023

Extracellular vesicles (EVs) are nano-sized vehicles secreted by all live cells to establish communication with adjacent cells. In recent years, mammalian EVs (MEVs) have been widely investigated for their therapeutic implications in human disease co...

  • Review
  • Open Access
18 Citations
5,137 Views
22 Pages

2 November 2023

Antimicrobial peptides (AMPs) have emerged as a promising class of bioactive molecules with the potential to combat infections associated with medical implants and biomaterials. This review article aims to provide a comprehensive analysis of the role...

  • Article
  • Open Access
4 Citations
3,119 Views
13 Pages

Development and Functionalization of a Novel Chitosan-Based Nanosystem for Enhanced Drug Delivery

  • Carmen Grierosu,
  • Gabriela Calin,
  • Daniela Damir,
  • Constantin Marcu,
  • Radu Cernei,
  • Georgeta Zegan,
  • Daniela Anistoroaei,
  • Mihaela Moscu,
  • Elena Mihaela Carausu and
  • Letitia Doina Duceac
  • + 5 authors

1 November 2023

Nowadays, infection diseases are one of the most significant threats to humans all around the world. An encouraging strategy for solving this issue and fighting resistant microorganisms is to develop drug carriers for a prolonged release of the antib...

  • Article
  • Open Access
5 Citations
2,630 Views
11 Pages

Poly(Aspartic Acid) Promotes Odontoblast-like Cell Differentiation in Rat Molars with Exposed Pulp

  • Fernanda Furuse Ventura dos Santos,
  • Stefan Habelitz,
  • Fábio Dupart Nascimento,
  • Victor Elias Arana-Chavez and
  • Roberto Ruggiero Braga

1 November 2023

In recent years, alternative pulpal therapies targeting dentinogenesis signaling pathways using different peptides have been investigated. The aim of this study was to verify the effectiveness of poly(aspartic acid), pAsp, in dentin regeneration usin...

  • Article
  • Open Access
4 Citations
5,078 Views
17 Pages

30 October 2023

In the field of healthcare and dentistry, 316L stainless steel is widely used for its corrosion resistance. However, the presence of lactic acid in salivary solutions can affect its surface reactivity. This study employed electrochemical methods to i...

  • Article
  • Open Access
9 Citations
2,873 Views
16 Pages

PCLLA-nanoHA Bone Substitute Promotes M2 Macrophage Polarization and Improves Alveolar Bone Repair in Diabetic Environments

  • Dandan Wang,
  • Ling Wei,
  • Jialin Hao,
  • Weifeng Tang,
  • Yuan Zhou,
  • Chenguang Zhang and
  • Jinming Wang

30 October 2023

The utilization of bioresorbable synthetic bone substitutes with immunomodulatory properties has gained significant attention in dental clinical applications for the absorption of alveolar bone induced by orthodontic treatment. In this study, we deve...

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J. Funct. Biomater. - ISSN 2079-4983Creative Common CC BY license