Previous Article in Journal
SPL-Based Modeling of Serrated Airfoil Noise via Functional Regression and Ensemble Learning
 
 
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Article

Optimal Control Strategies for a Mathematical Model of Pneumonia Infection

by
Nuwayyir Almutairi
and
Moustafa El-Shahed
*
Department of Mathematics, College of Science, Qassim University, P.O. Box 6644, Buraydah 51452, Saudi Arabia
*
Author to whom correspondence should be addressed.
Computation 2025, 13(9), 204; https://doi.org/10.3390/computation13090204 (registering DOI)
Submission received: 18 July 2025 / Revised: 11 August 2025 / Accepted: 22 August 2025 / Published: 23 August 2025
(This article belongs to the Section Computational Biology)

Abstract

In this study, we formulate and analyze a deterministic mathematical model describing the transmission dynamics of pneumonia. A comprehensive stability analysis is conducted for both the disease-free and endemic equilibrium points. The disease-free equilibrium is locally and globally asymptotically stable when the basic reproduction number R0 < 1, while the endemic equilibrium is locally and globally asymptotically stable when R0 > 1. To evaluate effective intervention strategies, an optimal control problem is formulated by introducing time-dependent control variables representing awareness campaigns, screening of carriers, and treatment of infected individuals. Applying Pontryagin’s Maximum Principle, the simulation results confirm the effectiveness of the proposed control strategies in reducing the number of infections and mitigating the overall disease burden. The findings offer valuable insights into the control of pneumonia and highlight the potential impact of strategic public health interventions.
Keywords: mathematical model; stability; pneumonia model; optimal control; forward bifurcation mathematical model; stability; pneumonia model; optimal control; forward bifurcation

Share and Cite

MDPI and ACS Style

Almutairi, N.; El-Shahed, M. Optimal Control Strategies for a Mathematical Model of Pneumonia Infection. Computation 2025, 13, 204. https://doi.org/10.3390/computation13090204

AMA Style

Almutairi N, El-Shahed M. Optimal Control Strategies for a Mathematical Model of Pneumonia Infection. Computation. 2025; 13(9):204. https://doi.org/10.3390/computation13090204

Chicago/Turabian Style

Almutairi, Nuwayyir, and Moustafa El-Shahed. 2025. "Optimal Control Strategies for a Mathematical Model of Pneumonia Infection" Computation 13, no. 9: 204. https://doi.org/10.3390/computation13090204

APA Style

Almutairi, N., & El-Shahed, M. (2025). Optimal Control Strategies for a Mathematical Model of Pneumonia Infection. Computation, 13(9), 204. https://doi.org/10.3390/computation13090204

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop