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Computation, Volume 12, Issue 5

2024 May - 23 articles

Cover Story: In injured arteries, platelets adhere to the subendothelium, initiating coagulation and forming a plug to stop blood loss. To study this process, we enhance a previous multiscale model by incorporating intraplatelet calcium regulation. In this framework, platelets are modeled as soft spheres that can attach, detach, activate, or become non-adhesive. Extracellular agonists like ADP and thrombin, along with platelet contact, stimulate the calcium pathway, leading to activation. Simulations reveal a contact-dependent activation threshold for thrombus core formation. Blocking P2Y receptors reduces the number of platelets in the thrombus shell. The model predicts that platelet size heterogeneity decreases overall platelet recruitment and can study antiplatelet therapy efficacy under various conditions. View this paper
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Articles (23)

  • Article
  • Open Access
1,811 Views
9 Pages

Microbolometer arrays, i.e., arrays of micro-scale pixels sensing temperature via resistance changes, have proven to be an effective basis for real-time imaging instrumentation in infrared as well as terahertz frequencies. In previous work, a design...

  • Article
  • Open Access
4,076 Views
17 Pages

Modeling Density Waves and Circulations in Vertical Cross-Section in Adhesive Contacts

  • Aleksander E. Filippov,
  • Iakov A. Lyashenko and
  • Valentin L. Popov

This work continues the study of the process of friction between a steel spherical indenter and a soft elastic elastomer previously published in our paper. It is done in the context of our previous experimental results obtained on systems with strong...

  • Article
  • Open Access
2,363 Views
18 Pages

Accelerating Conjugate Heat Transfer Simulations in Squared Heated Cavities through Graphics Processing Unit (GPU) Computing

  • César Augusto Borges da Silva Reis,
  • Daniel Botezelli,
  • Arthur Mendonça de Azevedo,
  • Elisan dos Santos Magalhães and
  • Aristeu da Silveira Neto

This research develops an innovative framework for accelerating Conjugate Heat Transfer (CHT) simulations within squared heated cavities through the application of Graphics Processing Units (GPUs). Although leveraging GPUs for computational speed imp...

  • Article
  • Open Access
1 Citations
2,261 Views
22 Pages

Short Fiber-Reinforced Polymer Polyamide 6 Lugs and Selective Laser-Melted Ti-6Al-4V Bushing Contact Cohesive Zone Model Mode II Parameters’ Evaluation

  • Andry Sedelnikov,
  • Evgenii Kurkin,
  • Vitaliy Smelov,
  • Vladislava Chertykovtseva,
  • Vyacheslav Alekseev,
  • Andrey Gavrilov,
  • Evgenii Kishov,
  • Maksim Zvyagincev and
  • Sergey Chernyakin

This paper discusses an approach to estimating the parameters of the cohesive zone model (CZM) by mode II by extruding the bushing along the lug axis. This method of evaluation requires small samples, which is particularly relevant when investigating...

  • Article
  • Open Access
1 Citations
1,465 Views
33 Pages

Relation Models of Surface Parameters and Backscattering (or Radiation) Fields as a Tool for Solving Remote Sensing Problems

  • Kseniia Nezhalska,
  • Valerii Volosyuk,
  • Kostiantyn Bilousov,
  • Denys Kolesnikov and
  • Glib Cherepnin

In this paper, an analysis of existing models for describing surfaces of various types is performed, and the possibilities of their application at the level of mathematical modeling are analyzed. Moreover, due to the large number of models and the co...

  • Article
  • Open Access
4 Citations
1,658 Views
15 Pages

The paper is devoted to the comparative analysis of different CFD techniques used to solve the problem of high-pressure hydrogen release into the air. Three variations of a contemporary low-dissipation numerical technique (CABARET) are compared with...

  • Article
  • Open Access
1 Citations
2,112 Views
19 Pages

This paper presents the design and development of an electronic controller for accurate temperature management for the storage of biological and chemical samples in healthcare applications. In the introduction, some important application aspects rela...

  • Article
  • Open Access
9 Citations
3,661 Views
24 Pages

Unveiling AI-Generated Financial Text: A Computational Approach Using Natural Language Processing and Generative Artificial Intelligence

  • Muhammad Asad Arshed,
  • Ștefan Cristian Gherghina,
  • Christine Dewi,
  • Asma Iqbal and
  • Shahzad Mumtaz

This study is an in-depth exploration of the nascent field of Natural Language Processing (NLP) and generative Artificial Intelligence (AI), and it concentrates on the vital task of distinguishing between human-generated text and content that has bee...

  • Article
  • Open Access
2 Citations
1,850 Views
16 Pages

Quasi-interpolation is a powerful tool for approximating functions using radial basis functions (RBFs) such as Gaussian kernels. This avoids solving large systems of equations as in RBF interpolation. However, quasi-interpolation with Gaussian kernel...

  • Article
  • Open Access
3 Citations
2,978 Views
19 Pages

In injured arteries, platelets adhere to the subendothelium and initiate the coagulation process. They recruit other platelets and form a plug that stops blood leakage. The formation of the platelet plug depends on platelet activation, a process that...

  • Article
  • Open Access
3 Citations
3,781 Views
11 Pages

Over-capacity flight scheduling by commercial airlines due to the surging demand in recent years creates congestion and significant delays at major airports. This attitude towards maximizing throughput calls for tactical flight rescheduling to comply...

  • Review
  • Open Access
7 Citations
4,175 Views
35 Pages

Review of Modeling Approaches for Conjugate Heat Transfer Processes in Oil-Immersed Transformers

  • Ivan Smolyanov,
  • Evgeniy Shmakov,
  • Denis Butusov and
  • Alexandra I. Khalyasmaa

This review addresses the modeling approaches for heat transfer processes in oil-immersed transformer. Electromagnetic, thermal, and hydrodynamic thermal fields are identified as the most critical aspects in describing the state of the transformer. T...

  • Article
  • Open Access
1 Citations
2,748 Views
20 Pages

Single-board computers (SBCs) are emerging as an efficient and economical solution for fog and edge computing, providing localized big data processing with lower energy consumption. Newer and faster SBCs deliver improved performance while still maint...

  • Article
  • Open Access
1 Citations
1,739 Views
25 Pages

This paper establishes a connection between control theory for partially observed discrete-event systems (DESs) and automated theorem proving (ATP) in the calculus of positively constructed formulas (PCFs). The language of PCFs is a complete first-or...

  • Article
  • Open Access
2,438 Views
25 Pages

To Bind or Not to Bind? A Comprehensive Characterization of TIR1 and Auxins Using Consensus In Silico Approaches

  • Fernando D. Prieto-Martínez,
  • Jennifer Mendoza-Cañas and
  • Karina Martínez-Mayorga

Auxins are chemical compounds of wide interest, mostly due to their role in plant metabolism and development. Synthetic auxins have been used as herbicides for more than 75 years and low toxicity in humans is one of their most advantageous features....

  • Article
  • Open Access
2 Citations
2,072 Views
16 Pages

This study explores a technique for enhancing the punching strength of reinforced concrete (RC) flat slabs, namely carbon fiber reinforced polymer (CFRP). Four large-scale RC flat slabs were fabricated, to assess the efficacy of this strengthening me...

  • Article
  • Open Access
1 Citations
2,426 Views
19 Pages

Numerical Estimation of Nonlinear Thermal Conductivity of SAE 1020 Steel

  • Ariel Flores Monteiro de Oliveira,
  • Elisan dos Santos Magalhães,
  • Kahl Dick Zilnyk,
  • Philippe Le Masson and
  • Ernandes José Gonçalves do Nascimento

Thermally characterizing high-thermal conductivity materials is challenging, especially considering high temperatures. However, the modeling of heat transfer processes requires specific material information. The present study addresses an inverse app...

  • Article
  • Open Access
3 Citations
1,664 Views
16 Pages

Minimizing the Number of Distrustful Nodes on the Path of IP Packet Transmission

  • Kvitoslava Obelovska,
  • Oleksandr Tkachuk and
  • Yaromyr Snaichuk

One of the important directions for improving modern Wide Area Networks is efficient and secure packet routing. Efficient routing is often based on using the shortest paths, while ensuring security involves preventing the possibility of packet interc...

  • Article
  • Open Access
1,844 Views
15 Pages

While there are multiple methods to ventilate protective clothing, there is still room for improvement. In our research, we are using ventilation elements that are positioned at the ventilation holes in the air space between the body and clothing. Th...

  • Article
  • Open Access
1 Citations
1,888 Views
14 Pages

Analysis of a Novel Method for Generating 3D Mesh at Contact Points in Packed Beds

  • Daniel F. Szambien,
  • Maximilian R. Ziegler,
  • Christoph Ulrich and
  • Roland Scharf

This study comprehensively analyzes the impact of the novel HybridBridge method, developed by the authors, for generating a 3D mesh at contact points within packed beds within the effective thermal conductivity. It compares HybridBridge with alternat...

  • Article
  • Open Access
5 Citations
2,733 Views
12 Pages

Torque Calculation and Dynamical Response in Halbach Array Coaxial Magnetic Gears through a Novel Analytical 2D Model

  • Panteleimon Tzouganakis,
  • Vasilios Gakos,
  • Christos Kalligeros,
  • Christos Papalexis,
  • Antonios Tsolakis and
  • Vasilios Spitas

Coaxial magnetic gears have piqued the interest of researchers due to their numerous benefits over mechanical gears. These include reduced noise and vibration, enhanced efficiency, lower maintenance costs, and improved backdrivability. However, their...

  • Article
  • Open Access
11 Citations
1,964 Views
19 Pages

The main objective of this paper is to propose a new boundary element method (BEM) modeling for stress sensitivity of nonlocal thermo-elasto-plastic damage problems. The numerical solution of the heat conduction equation subjected to a non-local cond...

  • Article
  • Open Access
3 Citations
2,446 Views
21 Pages

The effective control of any technological process is essential in ensuring high-quality finished products. This is particularly true in manufacturing knowledge-intensive and high-tech products, including microstructured photonic crystal fibers (PCF)...

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Computation - ISSN 2079-3197