Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data
Abstract
1. Introduction
2. Methods
2.1. Epidemiological Data
2.2. Statistical Model
3. Results
4. Discussion
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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Incubation Period Excluding WR (Days) | Incubation Period Including WR (Days) | Onset to Hospital Admission, Living (Days) | Onset to Hospital Admission, Deceased (Days) | Onset to Death (Days) | Hospital Admission to Death (Days) | |
---|---|---|---|---|---|---|
Number of cases | 52 cases | 158 cases | 155 cases | 34 cases | 34 cases | 39 cases |
Lognormal | ||||||
Mean | 5.0 (4.2, 6.0) | 5.6 (5.0, 6.3) | 3.9 (2.9, 5.3) | 6.2 (5.0, 7.8) | 14.5 (12.5, 17.0) | 8.6 (6.8, 10.8) |
SD | 3.0 (2.1, 4.5) | 2.8 (2.2, 3.6) | 9.1 (5.2, 16.3) | 4.3 (2.9, 6.6) | 6.7 (4.9, 9.4) | 6.7 (4.5, 10.3) |
5% | 1.7 (1.2, 2.3) | 2.3 (1.9, 2.7) | 0.2 (0.1, 0.3) | 1.9 (1.2, 2.5) | 6.5 (4.9, 7.9) | 2.2 (1.5, 3.0) |
Median | 4.3 (3.5, 5.1) | 5.0 (4.4, 5.6) | 1.5 (1.2, 1.9) | 5.1 (4.1, 6.3) | 13.2 (11.3, 15.3) | 6.7 (5.3, 8.3) |
95% | 10.6 (8.5, 14.1) | 10.8 (9.3, 12.9) | 14.0 (10.3, 20.1) | 13.9 (10.8, 19.6) | 26.8 (22.3, 34.5) | 20.5 (15.7, 28.7) |
99% | 15.4 (11.7, 22.5) | 14.9 (12.3, 18.7) | 35.0 (23.2, 56.9) | 21.1 (15.3, 32.8) | 36.0 (28.6, 49.8) | 32.6 (23.3, 50.1) |
WAIC | 257.2 | 859.6 | 693.5 | 183.9 | 221.9 | 240.1 |
Weight | 1.00 | 1.00 | 0.00 | 0.33 | 1.00 | 0.02 |
Weibull | ||||||
Mean | 5.4 (4.3, 6.6) | 5.8 (5.2, 6.5) | 3.4 (2.7, 4.2) | 6.5 (5.2, 8.0) | 15.1 (12.7, 17.8) | 8.9 (7.3, 10.4) |
SD | 3.6 (2.8, 4.7) | 2.8 (2.3, 3.5) | 4.4 (3.3, 6.0) | 4.0 (3.1, 5.4) | 7.6 (6.1, 9.7) | 5.4 (4.2, 7.3) |
5% | 0.9 (0.5, 1.4) | 2.1 (1.5, 2.6) | 0.1 (0.0, 0.1) | 1.9 (1.2, 2.5) | 4.2 (2.5, 6.0) | 1.7 (0.9, 2.7) |
Median | 4.7 (3.6, 5.8) | 5.3 (4.7, 6.0) | 1.8 (1.4, 2.3) | 5.1 (4.1, 6.3) | 14.3 (11.8, 17.1) | 8.0 (6.2, 9.8) |
95% | 12.0 (9.8, 15.6) | 11.0 (9.6, 12.9) | 11.7 (9.3, 15.6) | 13.9 (10.8, 19.6) | 28.6 (24.5, 34.9) | 18.8 (15.5, 24.4) |
99% | 15.9 (12.8, 21.5) | 14.2 (12.1, 17.0) | 20.3 (15.3, 29.2) | 21.1 (15.3, 32.8) | 35.0 (29.5, 44.4) | 24.2 (19.5, 33.0) |
WAIC | 273.8 | 871.8 | 662.4 | 185.5 | 231.3 | 236.1 |
Weight | 0.00 | 0.00 | 0.00 | 0.29 | 0.00 | 0.96 |
Gamma | ||||||
Mean | 5.3 (4.3, 6.6) | 6.0 (5.3, 6.7) | 3.3 (2.7, 4.0) | 6.5 (5.2, 8.0) | 15.0 (12.8, 17.5) | 8.8 (7.2, 10.8) |
SD | 3.2 (2.4, 4.3) | 3.1 (2.7, 3.7) | 4.2 (3.3, 5.4) | 4.0 (2.9, 5.6) | 6.9 (5.2, 9.1) | 5.7 (4.3, 7.8) |
5% | 1.4 (0.7, 2.0) | 1.5 (1.1, 2.0) | 0.0 (0.0, 0.1) | 1.6 (0.8, 2.4) | 5.8 (3.9, 7.6) | 1.9 (1.0, 2.9) |
Median | 4.7 (3.8, 5.7) | 5.6 (4.9, 6.4) | 1.7 (1.2, 2.2) | 5.6 (4.5, 6.9) | 13.9 (11.8, 17.1) | 7.6 (6.0, 9.3) |
95% | 11.3 (9.2, 14.5) | 11.7 (10.3, 13.4) | 11.6 (9.4, 14.7) | 13.8 (11.1, 18.6) | 27.4 (23.2, 34.1) | 19.9 (15.7, 25.7) |
99% | 15.2 (12.0, 20.2) | 14.5 (12.6, 16.9) | 19.4 (15.4, 25.1) | 18.6 (14.6, 26.2) | 34.9 (28.8, 44.8) | 26.8 (21.1, 36.5) |
WAIC | 265.8 | 895.9 | 656.6 | 183.4 | 225.1 | 236.3 |
Weight | 0.00 | 0.00 | 1.00 | 0.38 | 0.00 | 0.02 |
Lognormal | Incubation Period Excluding WR (Days) | Onset to Hospital Admission, Living (Days) | Onset to Hospital Admission, Deceased (Days) | Onset to Death (Days) | Hospital Admission to Death (Days) |
---|---|---|---|---|---|
Mean | 5.6 (4.4, 7.4) | 9.7 (5.4, 17.0) | 6.6 (5.2, 8.8) | 20.2 (15.1, 29.5) | 13.0 (8.7, 20.9) |
SD | 3.9 (2.4, 6.9) | 35.2 (12.9, 84.5) | 4.9 (3.0, 8.6) | 11.6 (6.6, 21.8) | 12.7 (6.4, 26.0) |
5% | 1.7 (1.1, 2.3) | 0.2 (0.1, 0.3) | 1.9 (1.2, 2.5) | 7.4 (5.6, 9.5) | 2.5 (1.6, 3.6) |
Median | 4.6 (3.7, 5.7) | 2.6 (1.9, 3.8) | 5.3 (4.2, 6.8) | 17.1 (13.5, 24.1) | 9.1 (6.7, 13.7) |
95% | 12.3 (9.1, 19.8) | 35.1 (20.5, 65.0) | 15.0 (11.2, 23.8) | 39.9 (27.9, 69.6) | 33.1 (20.9, 56.7) |
99% | 18.6 (12.7, 34.2) | 102.8 (52.8, 218.4) | 23.2 (16.0, 41.6) | 56.7 (37.0, 109.2) | 56.7 (32.5, 125.2) |
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Linton, N.M.; Kobayashi, T.; Yang, Y.; Hayashi, K.; Akhmetzhanov, A.R.; Jung, S.-m.; Yuan, B.; Kinoshita, R.; Nishiura, H. Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data. J. Clin. Med. 2020, 9, 538. https://doi.org/10.3390/jcm9020538
Linton NM, Kobayashi T, Yang Y, Hayashi K, Akhmetzhanov AR, Jung S-m, Yuan B, Kinoshita R, Nishiura H. Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data. Journal of Clinical Medicine. 2020; 9(2):538. https://doi.org/10.3390/jcm9020538
Chicago/Turabian StyleLinton, Natalie M., Tetsuro Kobayashi, Yichi Yang, Katsuma Hayashi, Andrei R. Akhmetzhanov, Sung-mok Jung, Baoyin Yuan, Ryo Kinoshita, and Hiroshi Nishiura. 2020. "Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data" Journal of Clinical Medicine 9, no. 2: 538. https://doi.org/10.3390/jcm9020538
APA StyleLinton, N. M., Kobayashi, T., Yang, Y., Hayashi, K., Akhmetzhanov, A. R., Jung, S.-m., Yuan, B., Kinoshita, R., & Nishiura, H. (2020). Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data. Journal of Clinical Medicine, 9(2), 538. https://doi.org/10.3390/jcm9020538