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Management of Sickle Cell Disease Pain among Adolescent and Pediatric Patients

Department of clinical pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan
Department of Pharmacology, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan
Department of Pediatrics, Princess Rahma Teaching Hospital, Irbid 21110, Jordan
Author to whom correspondence should be addressed.
Brain Sci. 2019, 9(8), 182;
Received: 25 June 2019 / Revised: 24 July 2019 / Accepted: 28 July 2019 / Published: 30 July 2019
(This article belongs to the Collection Collection on Systems Neuroscience)
PDF [480 KB, uploaded 30 July 2019]


Management of sickle cell pain in adolescent and pediatric patients is inadequate, and the employment of proper management guidelines and practices are highly variable among different regions and populations. APPT, the multidimensional adolescent pediatric pain tool, promotes optimal pain management and introduces best practical guidelines for pain management. The goal of this study is to assess pain and pain management among young patients diagnosed with sickle cell disease (SCD) by introducing the APPT as a tool for pain management, and analyze factors contributing to pain management. Information relevant to demographic data, SCD characteristics, APPT assessment, and satisfaction of patients regarding pain management were collected using a structured questionnaire. Results showed that SCD is highly associated with gender (p = 0.022), consanguinity (p = 0.012), and number of surgeries (p = 0.013). Most patients (58.9%) indicated the involvement of more than six body areas affected during pain crisis. Severe pain was described by more than half the patients (55.6%), while moderate pain was reported by 31.1%. Most patients described their pain by sensory, affective, and temporal words. The number of painful areas, pain intensity, and use of descriptive pain words was correlated and interpreted by age, BMI, school absence, and number of surgeries. Results of this study could provide guidance to healthcare providers to improve current practices for SCD pain management in order to improve health outcomes and patients’ satisfaction. View Full-Text
Keywords: assessment; APPT; Jordan; healthcare; hospital assessment; APPT; Jordan; healthcare; hospital

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Abdo, S.; Nuseir, K.Q.; Altarifi, A.A.; Barqawi, M.; Ayoub, N.M.; Mukkatash, T.L. Management of Sickle Cell Disease Pain among Adolescent and Pediatric Patients. Brain Sci. 2019, 9, 182.

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