Next Article in Journal
Effect of Treadmill Exercise and Trans-Cinnamaldehyde against d-Galactose- and Aluminum Chloride-Induced Cognitive Dysfunction in Mice
Next Article in Special Issue
A Psychophysical Window onto the Subjective Experience of Compulsion
Previous Article in Journal
High-Intensity Interval Training Improves Cognitive Flexibility in Older Adults
Review

A Systematic Review of Behavioral, Physiological, and Neurobiological Cognitive Regulation Alterations in Obsessive-Compulsive Disorder

1
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057 Braga, Portugal
2
ICVS-3B’s PT Government Associate Laboratory, 4710-057 Braga/Guimarães, Portugal
3
Clinical Academic Center-Braga (2CA), 4710-243 Braga, Portugal
*
Author to whom correspondence should be addressed.
Brain Sci. 2020, 10(11), 797; https://doi.org/10.3390/brainsci10110797
Received: 21 September 2020 / Revised: 24 October 2020 / Accepted: 27 October 2020 / Published: 29 October 2020
(This article belongs to the Special Issue Obsessive–Compulsive Disorder: Latest Advances and Prospects)
Obsessive-compulsive disorder (OCD) is characterized by cognitive regulation deficits. However, the current literature has focused on executive functioning and emotional response impairments in this disorder. Herein, we conducted a systematic review of studies assessing the behavioral, physiological, and neurobiological alterations in cognitive regulation in obsessive-compulsive patients using the PubMed database. Most of the studies included explored behavioral (distress, arousal, and frequency of intrusive thoughts) and neurobiological measures (brain activity and functional connectivity) using affective cognitive regulation paradigms. Our results pointed to the advantageous use of reappraisal and acceptance strategies in contrast to suppression to reduce distress and frequency of intrusive thoughts. Moreover, we observed alterations in frontoparietal network activity during cognitive regulation. Our conclusions are limited by the inclusion of underpowered studies with treated patients. Nonetheless, our findings support the OCD impairments in cognitive regulation of emotion and might help to improve current guidelines for cognitive therapy. View Full-Text
Keywords: OCD; obsessive-compulsive; emotion; suppression; reappraisal; fMRI OCD; obsessive-compulsive; emotion; suppression; reappraisal; fMRI
Show Figures

Figure 1

MDPI and ACS Style

Ferreira, S.; Pêgo, J.M.; Morgado, P. A Systematic Review of Behavioral, Physiological, and Neurobiological Cognitive Regulation Alterations in Obsessive-Compulsive Disorder. Brain Sci. 2020, 10, 797. https://doi.org/10.3390/brainsci10110797

AMA Style

Ferreira S, Pêgo JM, Morgado P. A Systematic Review of Behavioral, Physiological, and Neurobiological Cognitive Regulation Alterations in Obsessive-Compulsive Disorder. Brain Sciences. 2020; 10(11):797. https://doi.org/10.3390/brainsci10110797

Chicago/Turabian Style

Ferreira, Sónia, José M. Pêgo, and Pedro Morgado. 2020. "A Systematic Review of Behavioral, Physiological, and Neurobiological Cognitive Regulation Alterations in Obsessive-Compulsive Disorder" Brain Sciences 10, no. 11: 797. https://doi.org/10.3390/brainsci10110797

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop