Next Article in Journal
The Comparative Study on Cutting Performance of Different-Structure Milling Cutters in Machining CFRP
Next Article in Special Issue
Preparation and Characterization of Bacterial Cellulose-Carbon Dot Hybrid Nanopaper for Potential Sensing Applications
Previous Article in Journal
Optimized Multiport DC/DC Converter for Vehicle Drivetrains: Topology and Design Optimization
Previous Article in Special Issue
Characteristics of Curcumin-Loaded Bacterial Cellulose Films and Anticancer Properties against Malignant Melanoma Skin Cancer Cells
Open AccessArticle

Novel Bionanocellulose/κ-Carrageenan Composites for Tissue Engineering

Institute of Technical Biochemistry, Lodz University of Technology, Stefanowskiego 4/10, 90-924 Lodz, Poland
Institute of General and Ecological Chemistry, Lodz University of Technology, Żeromskiego 116, 90-924 Lodz, Poland
Author to whom correspondence should be addressed.
Appl. Sci. 2018, 8(8), 1352;
Received: 26 June 2018 / Revised: 1 August 2018 / Accepted: 9 August 2018 / Published: 12 August 2018
(This article belongs to the Special Issue Bacterial Cellulose Composites)
In this work, novel bacterial cellulose/κ-carrageenan (BNC/κ-Car) composites, being potential scaffolds for tissue engineering (TE), and outperforming the two polymers when used as scaffolds separately, were for the first time obtained using an in situ method, based on the stationary culture of bacteria Komagateibacter xylinus E25. The composites were compared with native BNC in terms of the morphology of fibers, chemical composition, crystallinity, tensile and compression strength, water holding capacity, water retention ratio and swelling properties. Murine chondrogenic ATDC5 cells were applied to assess the utility of the BNC/κ-Car composites as potential scaffolds. The impact of the composites on the cells viability, chondrogenic differentiation, and expression patterns of Col1α1, Col2α1, Runx2, and Sox9, which are indicative of ATDC5 chondrogenic differentiation, was determined. None of the composites obtained in this study caused the chondrocyte hypertrophy. All of them supported the differentiation of ATDC5 cells to more chondrogenic phenotype. View Full-Text
Keywords: bacterial cellulose; κ-carrageenan; composite; tissue engineering; chondrocytes bacterial cellulose; κ-carrageenan; composite; tissue engineering; chondrocytes
Show Figures

Figure 1

MDPI and ACS Style

Cielecka, I.; Szustak, M.; Gendaszewska-Darmach, E.; Kalinowska, H.; Ryngajłło, M.; Maniukiewicz, W.; Bielecki, S. Novel Bionanocellulose/κ-Carrageenan Composites for Tissue Engineering. Appl. Sci. 2018, 8, 1352.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop