Improvement of Mechanical Performance of Bioresorbable Magnesium Alloy Coronary Artery Stents through Stent Pattern Redesign
1
State Key Lab of Tribology, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China
2
Shanghai Bio-heart Biological Technology Co. Ltd., Shanghai 201201, China
3
Department of Biomechanical Engineering, Delft University of Technology, 2628 CD Delft, The Netherlands
*
Authors to whom correspondence should be addressed.
Appl. Sci. 2018, 8(12), 2461; https://doi.org/10.3390/app8122461
Received: 1 November 2018 / Revised: 23 November 2018 / Accepted: 25 November 2018 / Published: 2 December 2018
(This article belongs to the Special Issue Permanent and Long-Term Biodegradable Biomaterials)
Optimized stent pattern design can effectively enhance the mechanical performance of magnesium alloy stents by adjusting strain distribution and evolution during stent deformation, thereby overcoming the limitations imposed by the intrinsic mechanical properties of magnesium alloys. In the present study, a new stent design pattern for magnesium alloys was proposed and compared to two existing stent design patterns. Measures of the mechanical performance of these three stents, including crimping and expanding deformability, radial scaffolding capacity, radial recoil and bending flexibility, were determined. Three-dimensional finite element (FE) models were built to predict the mechanical performance of the stents with the three design patterns and to assist in understanding the experimental results. The results showed that, overall, the stent with the new design pattern was superior to the stents based on the existing designs, though the expanding capacity of the newly designed stent still needed to be improved.
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Keywords:
bioresorbable stent; magnesium; mechanical property; deformation behavior; finite element analysis
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
MDPI and ACS Style
Wang, Q.; Fang, G.; Zhao, Y.-H.; Zhou, J. Improvement of Mechanical Performance of Bioresorbable Magnesium Alloy Coronary Artery Stents through Stent Pattern Redesign. Appl. Sci. 2018, 8, 2461. https://doi.org/10.3390/app8122461
AMA Style
Wang Q, Fang G, Zhao Y-H, Zhou J. Improvement of Mechanical Performance of Bioresorbable Magnesium Alloy Coronary Artery Stents through Stent Pattern Redesign. Applied Sciences. 2018; 8(12):2461. https://doi.org/10.3390/app8122461
Chicago/Turabian StyleWang, Qian; Fang, Gang; Zhao, Ying-Hong; Zhou, Jie. 2018. "Improvement of Mechanical Performance of Bioresorbable Magnesium Alloy Coronary Artery Stents through Stent Pattern Redesign" Appl. Sci. 8, no. 12: 2461. https://doi.org/10.3390/app8122461
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