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Article

Theoretical and Practical Knowledge Regarding Infective Endocarditis Prevention Among Dentists and Physicians: A Questionnaire-Based Survey

by
Claudia Salerno
1,2,
Silvia Cirio
1,
Nicole Camoni
1,3,
Guglielmo Campus
4,5,6 and
Maria Grazia Cagetti
1,*
1
Department of Biomedical, Surgical and Dental Sciences, University of Milan, Via Beldiletto 1, 20142 Milan, Italy
2
Graduate School for Health Sciences, University of Bern, 3012 Bern, Switzerland
3
Asst Valle Olona, Dental Unit, Via Eusebio Pastori 4, 21013 Gallarate, Italy
4
Department of Cariology, Institute of Odontology, Sahlgrenska Academin, University of Gothenburg, Medicinaregatan 12 E, 413 90 Gothenburg, Sweden
5
Department of Cariology, Saveetha Dental College and Hospitals (SIMATS), No. 162, Poonamallee High Road, Velappanchavadi, 600 077 Chennai, India
6
Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Via Caserta 6, 00161 Rome, Italy
*
Author to whom correspondence should be addressed.
Appl. Sci. 2025, 15(17), 9532; https://doi.org/10.3390/app15179532 (registering DOI)
Submission received: 21 July 2025 / Revised: 25 August 2025 / Accepted: 28 August 2025 / Published: 29 August 2025

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This study highlights existing gaps in the appropriate use of endocarditis prophylaxis for invasive dental and non-dental medical procedures among dentists and physicians, particularly regarding risk assessment and adherence to current guidelines. The findings underscore the need for enhanced education and clearer clinical protocols to support accurate risk stratification, reducing missed prophylaxis in high-risk patients and minimizing unnecessary antibiotic use in low-risk individuals, with the overarching goal of preventing infective endocarditis and curbing antibiotic resistance.

Abstract

Infective endocarditis (IE) is a rare but potentially life-threatening infection, often triggered by invasive procedures, dental or otherwise, in at-risk individuals. This study aimed to assess the knowledge of IE prophylaxis among healthcare professionals, focusing on dentists and physicians. Two validated, anonymous questionnaires were emailed to 27,000 healthcare providers in the province of Milan (Italy). A total of 970 responses were collected (response rate just over 3%), with 49.2% from physicians and 50.8% from dentists. No significant differences were found between the two groups regarding years of experience or guideline usage (p > 0.05), although more physicians (12.7%) than dentists (6.7%) reported unfamiliarity with any guidelines. Physicians often misclassified the risk associated with certain cardiac conditions and overprescribed prophylaxis for low-risk procedures, with overall accuracy falling below the expected performance benchmark (H0: 58.0% ± 2.0%). Dentists showed a better understanding of high-risk dental procedures, yet performance remained suboptimal, with multiple scores below the expected benchmark (H0: 68.0% ± 2.0%). These findings highlight widespread knowledge gaps and inconsistent adherence to IE prophylaxis guidelines. The results align with international observations and emphasize the urgent need for continuing education and improved dissemination of evidence-based recommendations across medical and dental settings.
Keywords: infective endocarditis; prophylaxis guidelines; healthcare professionals; survey; knowledge assessment; dental practice; medical practice infective endocarditis; prophylaxis guidelines; healthcare professionals; survey; knowledge assessment; dental practice; medical practice

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MDPI and ACS Style

Salerno, C.; Cirio, S.; Camoni, N.; Campus, G.; Cagetti, M.G. Theoretical and Practical Knowledge Regarding Infective Endocarditis Prevention Among Dentists and Physicians: A Questionnaire-Based Survey. Appl. Sci. 2025, 15, 9532. https://doi.org/10.3390/app15179532

AMA Style

Salerno C, Cirio S, Camoni N, Campus G, Cagetti MG. Theoretical and Practical Knowledge Regarding Infective Endocarditis Prevention Among Dentists and Physicians: A Questionnaire-Based Survey. Applied Sciences. 2025; 15(17):9532. https://doi.org/10.3390/app15179532

Chicago/Turabian Style

Salerno, Claudia, Silvia Cirio, Nicole Camoni, Guglielmo Campus, and Maria Grazia Cagetti. 2025. "Theoretical and Practical Knowledge Regarding Infective Endocarditis Prevention Among Dentists and Physicians: A Questionnaire-Based Survey" Applied Sciences 15, no. 17: 9532. https://doi.org/10.3390/app15179532

APA Style

Salerno, C., Cirio, S., Camoni, N., Campus, G., & Cagetti, M. G. (2025). Theoretical and Practical Knowledge Regarding Infective Endocarditis Prevention Among Dentists and Physicians: A Questionnaire-Based Survey. Applied Sciences, 15(17), 9532. https://doi.org/10.3390/app15179532

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