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Review

Lignin Waste Valorization in the Bioeconomy Era: Toward Sustainable Innovation and Climate Resilience

by
Alfonso Trezza
1,*,
Linta Mahboob
1,
Anna Visibelli
1,
Michela Geminiani
1,2 and
Annalisa Santucci
1,2,3
1
ONE-HEALTH Lab, Department of Biotechnology Chemistry Pharmacy, University of Siena, Via Aldo Moro, 2, 53100 Siena, Italy
2
SienabioACTIVE, University of Siena, Via Aldo Moro, 2, 53100 Siena, Italy
3
MetabERN, University of Siena, Via Aldo Moro, 2, 53100 Siena, Italy
*
Author to whom correspondence should be addressed.
Appl. Sci. 2025, 15(14), 8038; https://doi.org/10.3390/app15148038
Submission received: 10 June 2025 / Revised: 10 July 2025 / Accepted: 17 July 2025 / Published: 18 July 2025
(This article belongs to the Special Issue Biosynthesis and Applications of Natural Products)

Abstract

Lignin, the most abundant renewable aromatic biopolymer on Earth, is rapidly emerging as a powerful enabler of next-generation sustainable technologies. This review shifts the focus to the latest industrial breakthroughs that exploit lignin’s multifunctional properties across energy, agriculture, healthcare, and environmental sectors. Lignin-derived carbon materials are offering scalable, low-cost alternatives to critical raw materials in batteries and supercapacitors. In agriculture, lignin-based biostimulants and controlled-release fertilizers support resilient, low-impact food systems. Cosmetic and pharmaceutical industries are leveraging lignin’s antioxidant, UV-protective, and antimicrobial properties to create bio-based, clean-label products. In water purification, lignin-based adsorbents are enabling efficient and biodegradable solutions for persistent pollutants. These technological leaps are not merely incremental, they represent a paradigm shift toward a materials economy powered by renewable carbon. Backed by global sustainability roadmaps like the European Green Deal and China’s 14th Five-Year Plan, lignin is moving from industrial residue to strategic asset, driven by unprecedented investment and cross-sector collaboration. Breakthroughs in lignin upgrading, smart formulation, and application-driven design are dismantling long-standing barriers to scale, performance, and standardization. As showcased in this review, lignin is no longer just a promising biopolymer, it is a catalytic force accelerating the global transition toward circularity, climate resilience, and green industrial transformation. The future of sustainable innovation is lignin-enabled.
Keywords: lignin valorization; sustainable bioeconomy; circular economy; renewable resources; lignocellulosic biomass; greenhouse gas reduction; bio-based materials; industrial applications; waste-to-value; climate change mitigation lignin valorization; sustainable bioeconomy; circular economy; renewable resources; lignocellulosic biomass; greenhouse gas reduction; bio-based materials; industrial applications; waste-to-value; climate change mitigation

Share and Cite

MDPI and ACS Style

Trezza, A.; Mahboob, L.; Visibelli, A.; Geminiani, M.; Santucci, A. Lignin Waste Valorization in the Bioeconomy Era: Toward Sustainable Innovation and Climate Resilience. Appl. Sci. 2025, 15, 8038. https://doi.org/10.3390/app15148038

AMA Style

Trezza A, Mahboob L, Visibelli A, Geminiani M, Santucci A. Lignin Waste Valorization in the Bioeconomy Era: Toward Sustainable Innovation and Climate Resilience. Applied Sciences. 2025; 15(14):8038. https://doi.org/10.3390/app15148038

Chicago/Turabian Style

Trezza, Alfonso, Linta Mahboob, Anna Visibelli, Michela Geminiani, and Annalisa Santucci. 2025. "Lignin Waste Valorization in the Bioeconomy Era: Toward Sustainable Innovation and Climate Resilience" Applied Sciences 15, no. 14: 8038. https://doi.org/10.3390/app15148038

APA Style

Trezza, A., Mahboob, L., Visibelli, A., Geminiani, M., & Santucci, A. (2025). Lignin Waste Valorization in the Bioeconomy Era: Toward Sustainable Innovation and Climate Resilience. Applied Sciences, 15(14), 8038. https://doi.org/10.3390/app15148038

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