Resurgence of Bordetella pertussis in Lazio: A Cross-Age Surveillance Study from Two Referral Hospitals
Abstract
1. Introduction
2. Materials and Methods
2.1. Adult Population
2.2. Pediatric Population
2.3. Statistical Analyses
3. Results
Trend and Regression Analysis
4. Discussion
5. Limitations of This Study
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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2019 | 2020 | 2021 | 2022 | 2023 | 2024 | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
NPS 1 | LRTS 2 | NPS | LRTS | NPS | LRTS | NPS | LRTS | NPS | LRTS | NPS | LRTS | |
P 3/T 4 | P/T | P/T | P/T | P/T | P/T | P/T | P/T | P/T | P/T | P/T | P/T | |
January | 1/80 | 0/16 | 1/158 | 0/10 | 0/92 | 0/10 | 0/76 | 0/14 | 0/159 | 0/25 | 1/168 | 0/53 |
February | 0/74 | 0/22 | 0/332 | 0/7 | 0/170 | 0/11 | 0/62 | 0/17 | 2/151 | 0/17 | 0/34 | 0/39 |
March | 0/55 | 0/8 | 2/398 | 0/11 | 0/307 | 0/10 | 0/83 | 0/17 | 1/102 | 0/19 | 0/60 | 0/46 |
April | 0/30 | 0/10 | 0/224 | 0/6 | 0/139 | 0/12 | 0/90 | 0/17 | 0/83 | 0/18 | 1/65 | 0/45 |
May | 0/23 | 0/12 | 1/213 | 0/14 | 0/109 | 0/9 | 0/52 | 0/35 | 0/81 | 0/20 | 2/99 | 0/38 |
June | 1/25 | 0/7 | 0/78 | 0/1 | 0/87 | 0/15 | 0/38 | 0/13 | 0/70 | 0/15 | 4/113 | 0/19 |
July | 0/13 | 0/3 | 0/85 | 0/9 | 0/63 | 0/13 | 0/63 | 0/9 | 0/68 | 0/7 | 1/106 | 0/9 |
August | 0/10 | 0/4 | 0/29 | 0/4 | 0/62 | 0/7 | 0/56 | 0/14 | 0/64 | 0/17 | 0/112 | 0/22 |
September | 0/18 | 0/1 | 0/97 | 0/3 | 0/52 | 0/12 | 0/55 | 0/13 | 0/60 | 0/11 | 0/116 | 0/20 |
October | 0/32 | 0/6 | 0/114 | 0/1 | 0/71 | 0/12 | 0/91 | 0/7 | 0/66 | 0/5 | 2/154 | 1/18 |
November | 0/44 | 0/1 | 0/101 | 0/0 | 0/106 | 0/9 | 0/76 | 0/12 | 0/86 | 0/16 | 0/145 | 0/24 |
December | 1/54 | 0/7 | 0/123 | 0/0 | 0/93 | 0/9 | 0/106 | 0/15 | 0/143 | 0/17 | 0/237 | 0/21 |
Total | 3/458 | 0/97 | 4/1952 | 0/66 | 0/1351 | 0/129 | 0/848 | 0/183 | 3/1133 | 0/187 | 11/1408 | 1/355 |
3/555 | 4/2018 | 0/1480 | 0/1031 | 3/1320 | 12/1763 |
2019 | 2020 | 2021 | 2022 | 2023 | 2024 | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
NPS 1 | LRTS 2 | NPS | LRTS | NPS | LRTS | NPS | LRTS | NPS | LRTS | NPS | LRTS | |
P 3/T 4 | P/T | P/T | P/T | P/T | P/T | P/T | P/T | P/T | P/T | P/T | P/T | |
January | 0/5 | 4/208 | 0/28 | 8/133 | 0/1 | 0/7 | 0/0 | 0/18 | 0/6 | 0/37 | 0/7 | 5/29 |
February | 0/4 | 1/152 | 2/57 | 3/83 | 0/1 | 0/12 | 0/0 | 0/12 | 0/1 | 0/11 | 0/1 | 4/20 |
March | 1/6 | 3/121 | 0/30 | 2/42 | 0/3 | 0/10 | 0/6 | 0/9 | 0/3 | 0/18 | 1/8 | 7/36 |
April | 0/1 | 6/81 | 0/10 | 1/13 | 0/1 | 0/8 | 0/0 | 0/12 | 0/1 | 0/12 | 3/13 | 9/25 |
May | 0/2 | 5/62 | 0/0 | 0/5 | 0/0 | 0/17 | 0/1 | 0/12 | 0/3 | 0/13 | 23/58 | 11/29 |
June | 0/1 | 3/43 | 0/4 | 1/17 | 0/0 | 0/11 | 0/2 | 0/6 | 0/1 | 0/8 | 38/115 | 8/29 |
July | 1/3 | 4/20 | 0/2 | 0/11 | 0/2 | 0/6 | 0/1 | 0/3 | 0/7 | 0/6 | 38/122 | 2/20 |
August | 4/6 | 2/21 | 0/1 | 0/21 | 0/1 | 0/7 | 0/0 | 0/6 | 1/6 | 1/5 | 22/66 | 7/25 |
September | 1/3 | 3/30 | 0/5 | 0/15 | 0/1 | 0/4 | 0/1 | 0/9 | 0/8 | 0/10 | 17/73 | 6/22 |
October | 0/2 | 3/36 | 0/3 | 0/18 | 0/9 | 0/22 | 0/1 | 0/14 | 1/10 | 0/5 | 4/87 | 0/18 |
November | 0/13 | 0/63 | 0/1 | 0/18 | 0/25 | 0/64 | 0/5 | 0/25 | 0/3 | 0/11 | 1/71 | 0/22 |
December | 1/28 | 2/140 | 0/2 | 0/15 | 0/19 | 0/35 | 0/17 | 0/50 | 0/10 | 0/26 | 2/26 | 1/24 |
Total | 8/74 | 36/977 | 2/143 | 15/391 | 0/64 | 0/203 | 0/34 | 0/176 | 2/59 | 1/162 | 149/648 | 58/298 |
44/1051 | 17/534 | 0/267 | 0/210 | 3/221 | 207/946 |
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Sberna, G.; Linardos, G.; Lalle, E.; Scutari, R.; Vulcano, A.; Mija, C.; Bordi, L.; Bartolini, B.; Maggi, F.; Perno, C.F.; et al. Resurgence of Bordetella pertussis in Lazio: A Cross-Age Surveillance Study from Two Referral Hospitals. Microorganisms 2025, 13, 1808. https://doi.org/10.3390/microorganisms13081808
Sberna G, Linardos G, Lalle E, Scutari R, Vulcano A, Mija C, Bordi L, Bartolini B, Maggi F, Perno CF, et al. Resurgence of Bordetella pertussis in Lazio: A Cross-Age Surveillance Study from Two Referral Hospitals. Microorganisms. 2025; 13(8):1808. https://doi.org/10.3390/microorganisms13081808
Chicago/Turabian StyleSberna, Giuseppe, Giulia Linardos, Eleonora Lalle, Rossana Scutari, Antonella Vulcano, Cosmina Mija, Licia Bordi, Barbara Bartolini, Fabrizio Maggi, Carlo Federico Perno, and et al. 2025. "Resurgence of Bordetella pertussis in Lazio: A Cross-Age Surveillance Study from Two Referral Hospitals" Microorganisms 13, no. 8: 1808. https://doi.org/10.3390/microorganisms13081808
APA StyleSberna, G., Linardos, G., Lalle, E., Scutari, R., Vulcano, A., Mija, C., Bordi, L., Bartolini, B., Maggi, F., Perno, C. F., & Fontana, C. (2025). Resurgence of Bordetella pertussis in Lazio: A Cross-Age Surveillance Study from Two Referral Hospitals. Microorganisms, 13(8), 1808. https://doi.org/10.3390/microorganisms13081808