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Biological Activity of Quaternary Ammonium Salts and Their Derivatives

Department of Technology and Instrumental Analysis, Institute of Quality Science, Poznań University of Economics and Business, 61-875 Poznań, Poland
Department of Plant Pathology and Microbiology, National Taiwan University, Taipei 100, Taiwan
Author to whom correspondence should be addressed.
Pathogens 2020, 9(6), 459;
Received: 25 May 2020 / Revised: 5 June 2020 / Accepted: 8 June 2020 / Published: 10 June 2020
(This article belongs to the Section Human Pathogens)
Besides their positive role, microorganisms are related to a number of undesirable effects, including many diseases, biodeterioration and food spoilage, so when their presence is undesired, they must be controlled. Numerous biocides limiting the development of microorganisms have been proposed, however, in this paper the biocidal and inhibitory activity of quaternary ammonium salts (QASs) and their zwitterionic derivatives is addressed. This paper presents the current state of knowledge about the biocidal activity of QAS and their derivatives. Moreover, the known mechanisms of antimicrobial activity and the problem of emerging resistance to QAS are discussed. The latest trends in the study of surfactants and their potential use are also presented. View Full-Text
Keywords: quaternary ammonium salts; sulfobetaines; biocidal activity quaternary ammonium salts; sulfobetaines; biocidal activity
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MDPI and ACS Style

Kwaśniewska, D.; Chen, Y.-L.; Wieczorek, D. Biological Activity of Quaternary Ammonium Salts and Their Derivatives. Pathogens 2020, 9, 459.

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