Next Article in Journal
A Review of Temperature, pH, and Other Factors that Influence the Survival of Salmonella in Mayonnaise and Other Raw Egg Products
Next Article in Special Issue
Transcriptomic Analysis Reveals Selective Metabolic Adaptation of Streptococcus suis to Porcine Blood and Cerebrospinal Fluid
Previous Article in Journal
Molecular Epidemiology and Spatio-Temporal Dynamics of the H3N8 Equine Influenza Virus in South America
Previous Article in Special Issue
Clearance of Streptococcus suis in Stomach Contents of Differently Fed Growing Pigs
Open AccessCommunication

Distribution of Type I Restriction–Modification Systems in Streptococcus suis: An Outlook

1
Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
2
Department of Global Health-Amsterdam Institute for Global Health and Development, Academic Medical Center, University of Amsterdam, Pietersbergweg 17, 1105 BM Amsterdam, The Netherlands
*
Author to whom correspondence should be addressed.
Academic Editor: Mariela Segura
Pathogens 2016, 5(4), 62; https://doi.org/10.3390/pathogens5040062
Received: 18 July 2016 / Revised: 7 November 2016 / Accepted: 12 November 2016 / Published: 18 November 2016
(This article belongs to the Special Issue Streptococcus suis)
Streptococcus suis is a porcine commensal and pathogen with zoonotic potential. We recently identified a novel Type I restriction–modification (R–M) system in a zoonotic S. suis clone which has emerged in the Netherlands. Here, we describe the DNA inversions in the specificity subunit of this system in S. suis serotype 2, clonal complex 20 and explain the absence of domain movement by the absence of repeats. In addition, we identified a core Type I R–M system present in 95% of the isolates and found an association of the distribution of Type I R–M systems in the S. suis genome with population structure. We speculate on the potential role of Type I R–M systems in S. suis given the recently described associations of Type I R–M systems with virulence and propose future research directions. View Full-Text
Keywords: Streptococcus suis; prophage; Type I restriction–modification system; pfam; genomic analysis; DNA inversions Streptococcus suis; prophage; Type I restriction–modification system; pfam; genomic analysis; DNA inversions
Show Figures

Figure 1

MDPI and ACS Style

Willemse, N.; Schultsz, C. Distribution of Type I Restriction–Modification Systems in Streptococcus suis: An Outlook. Pathogens 2016, 5, 62.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop