Point-of-Care Diagnostic for Trichomonas vaginalis, the Most Prevalent, Non-Viral Sexually Transmitted Infection
Abstract
:1. Introduction
2. Materials and Methods
2.1. MedMira Rapid Vertical Flow (RVF®) Core Technology
2.2. Whole Blood for Testing for Antibodies to ACT::SOE3
2.3. α-Actinin and ACT::SOE3 and Monoclonal Antibodies (MAbs)
2.4. MAbs and α-Actinin Antibody in Serum for ACT::SOE3 Detection
2.5. Origin of Sera
2.6. Reproducibility
3. Results
3.1. RVF® Test Technology Cartridge and Single Analyte Detection Platform
3.2. Rapid Vertical Flow (RVF®) Test Package and Materials
3.3. Step-Wise Approach
3.4. Specific MAb Detection of ACT::SOE3
3.5. Cartridges with Positive Reactions to Different Sera
3.6. Use of Cartridges with Blood-Spiked Positive and Negative Sera
4. Discussion
5. Conclusions
6. Patents
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Alderete, J.F.; Chan, H. Point-of-Care Diagnostic for Trichomonas vaginalis, the Most Prevalent, Non-Viral Sexually Transmitted Infection. Pathogens 2023, 12, 77. https://doi.org/10.3390/pathogens12010077
Alderete JF, Chan H. Point-of-Care Diagnostic for Trichomonas vaginalis, the Most Prevalent, Non-Viral Sexually Transmitted Infection. Pathogens. 2023; 12(1):77. https://doi.org/10.3390/pathogens12010077
Chicago/Turabian StyleAlderete, John F., and Hermes Chan. 2023. "Point-of-Care Diagnostic for Trichomonas vaginalis, the Most Prevalent, Non-Viral Sexually Transmitted Infection" Pathogens 12, no. 1: 77. https://doi.org/10.3390/pathogens12010077
APA StyleAlderete, J. F., & Chan, H. (2023). Point-of-Care Diagnostic for Trichomonas vaginalis, the Most Prevalent, Non-Viral Sexually Transmitted Infection. Pathogens, 12(1), 77. https://doi.org/10.3390/pathogens12010077