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Open AccessPerspective

A Perspective on Microneedle-Based Drug Delivery and Diagnostics in Paediatrics

International Iberian Nanotechnology Laboratory, 4715-330 Braga, Portugal
University of Oviedo, 33006 Asturias, Spain
Department of Cell Biology and Immunology, Centro de Biología Molecular “Severo Ochoa”, 28049 Madrid, Spain
Author to whom correspondence should be addressed.
J. Pers. Med. 2019, 9(4), 49;
Received: 10 October 2019 / Revised: 4 November 2019 / Accepted: 12 November 2019 / Published: 15 November 2019
Microneedles (MNs) have been extensively explored in the literature as a means to deliver drugs in the skin, surpassing the stratum corneum permeability barrier. MNs are potentially easy to produce and may allow the self-administration of drugs without causing pain or bleeding. More recently, MNs have been investigated to collect/assess the interstitial fluid in order to monitor or detect specific biomarkers. The integration of these two concepts in closed-loop devices holds the promise of automated and minimally invasive disease detection/monitoring and therapy. These assure low invasiveness and, importantly, open a window of opportunity for the application of population-specific and personalised therapies. View Full-Text
Keywords: microneedles; medical devices; paediatrics microneedles; medical devices; paediatrics
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MDPI and ACS Style

Pires, L.R.; Vinayakumar, K.; Turos, M.; Miguel, V.; Gaspar, J. A Perspective on Microneedle-Based Drug Delivery and Diagnostics in Paediatrics. J. Pers. Med. 2019, 9, 49.

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