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Open AccessPerspective

A Perspective on Microneedle-Based Drug Delivery and Diagnostics in Paediatrics

1
International Iberian Nanotechnology Laboratory, 4715-330 Braga, Portugal
2
University of Oviedo, 33006 Asturias, Spain
3
Department of Cell Biology and Immunology, Centro de Biología Molecular “Severo Ochoa”, 28049 Madrid, Spain
*
Author to whom correspondence should be addressed.
J. Pers. Med. 2019, 9(4), 49; https://doi.org/10.3390/jpm9040049
Received: 10 October 2019 / Revised: 4 November 2019 / Accepted: 12 November 2019 / Published: 15 November 2019
Microneedles (MNs) have been extensively explored in the literature as a means to deliver drugs in the skin, surpassing the stratum corneum permeability barrier. MNs are potentially easy to produce and may allow the self-administration of drugs without causing pain or bleeding. More recently, MNs have been investigated to collect/assess the interstitial fluid in order to monitor or detect specific biomarkers. The integration of these two concepts in closed-loop devices holds the promise of automated and minimally invasive disease detection/monitoring and therapy. These assure low invasiveness and, importantly, open a window of opportunity for the application of population-specific and personalised therapies. View Full-Text
Keywords: microneedles; medical devices; paediatrics microneedles; medical devices; paediatrics
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Pires, L.R.; Vinayakumar, K.; Turos, M.; Miguel, V.; Gaspar, J. A Perspective on Microneedle-Based Drug Delivery and Diagnostics in Paediatrics. J. Pers. Med. 2019, 9, 49.

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