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J. Pers. Med. 2017, 7(4), 11; https://doi.org/10.3390/jpm7040011

Personomics: The Missing Link in the Evolution from Precision Medicine to Personalized Medicine

Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Received: 23 August 2017 / Revised: 23 September 2017 / Accepted: 9 October 2017 / Published: 16 October 2017
Full-Text   |   PDF [157 KB, uploaded 18 October 2017]

Abstract

Clinical practice guidelines have been developed for many common conditions based on data from randomized controlled trials. When medicine is informed solely by clinical practice guidelines, however, the patient is not treated as an individual, but rather a member of a group. Precision medicine, as defined herein, characterizes unique biological characteristics of the individual or of specimens obtained from an individual to tailor diagnostics and therapeutics to a specific patient. These unique biological characteristics are defined by the tools of precision medicine: genomics, proteomics, metabolomics, epigenomics, pharmacogenomics, and other “-omics.” Personalized medicine, as defined herein, uses additional information about the individual derived from knowing the patient as a person. These unique personal characteristics are defined by tools known as personomics which takes into account an individual’s personality, preferences, values, goals, health beliefs, social support network, financial resources, and unique life circumstances that affect how and when a given health condition will manifest in that person and how that condition will respond to treatment. In this paradigm, precision medicine may be considered a necessary step in the evolution of medical care to personalized medicine, with personomics as the missing link. View Full-Text
Keywords: personomics; precision medicine; health care; personalized medicine personomics; precision medicine; health care; personalized medicine
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Ziegelstein, R.C. Personomics: The Missing Link in the Evolution from Precision Medicine to Personalized Medicine. J. Pers. Med. 2017, 7, 11.

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