Risk of Cardiovascular Disease in Apnoeic Individuals: Role of Comorbid Insomnia Disorder
Erasme Hospital, Department of Psychiatry and Sleep Laboratory, Université Libre de Bruxelles, ULB, Route de Lennik, 808, Anderlecht, 1070 Brussels, Belgium
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Academic Editors: David Slouka and Milan Štengl
Life 2022, 12(7), 944; https://doi.org/10.3390/life12070944
Received: 29 April 2022
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Revised: 18 June 2022
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Accepted: 20 June 2022
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Published: 23 June 2022
(This article belongs to the Special Issue Obstructive Sleep Apnea Syndrome: History, Current Status, Perspectives)
Given the limited data available, the aim of this study was to examine the 10-year cardiovascular disease (CVD) risk associated with comorbid insomnia disorder and its specific subtypes in apnoeic individuals. Data from 1104 apnoeic individuals recruited from the database of the Erasme Hospital Sleep Laboratory were analysed. Only apnoeic individuals with a Framingham Risk Score ≥10% were included in the group at moderate-to-high 10-year CVD risk. Logistic regression analyses were conducted to examine the risk of 10-year CVD risk associated with comorbid insomnia disorder and its specific subtypes in apnoeic individuals. Moderate-to-high 10-year CVD risk was present in 59.6% of the apnoeic individuals in our sample. After adjustment for the main confounding factors, multivariate logistic regression analyses revealed that comorbid insomnia disorder and, more particularly, its subtype with short sleep duration were significantly associated with moderate-to-high 10-year CVD risk in apnoeic individuals. In this study, we demonstrate that comorbid insomnia disorder and, more specifically, its subtype with short sleep duration appear to have a negative cumulative effect on 10-year CVD risk in apnoeic individuals, which justifies more systematic research and adequate therapeutic management of this disorder to allow for better cardiovascular disease prevention in this particular subpopulation.
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Keywords:
cardiovascular risk; insomnia disorder; obstructive sleep apnoea syndrome; polysomnography
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
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MDPI and ACS Style
Hein, M.; Wacquier, B.; Lanquart, J.-P.; Loas, G. Risk of Cardiovascular Disease in Apnoeic Individuals: Role of Comorbid Insomnia Disorder. Life 2022, 12, 944. https://doi.org/10.3390/life12070944
AMA Style
Hein M, Wacquier B, Lanquart J-P, Loas G. Risk of Cardiovascular Disease in Apnoeic Individuals: Role of Comorbid Insomnia Disorder. Life. 2022; 12(7):944. https://doi.org/10.3390/life12070944
Chicago/Turabian StyleHein, Matthieu, Benjamin Wacquier, Jean-Pol Lanquart, and Gwenolé Loas. 2022. "Risk of Cardiovascular Disease in Apnoeic Individuals: Role of Comorbid Insomnia Disorder" Life 12, no. 7: 944. https://doi.org/10.3390/life12070944
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