The accurate prediction of Mediterranean tropical-like cyclones, or medicanes, is an important challenge for numerical weather prediction models due to their significant adverse impact on the environment, life, and property. The aim of this study is to investigate the sensitivity of an intense medicane, which formed south of Sicily on 7 November 2014, to the microphysical, cumulus, and boundary/surface layer schemes. The non-hydrostatic Weather Research and Forecasting model (version 3.7.1) is employed. A symmetric cyclone with a deep warm core, corresponding to a medicane, develops in all of the experiments, except for the one with the Thompson microphysics. There is a significant sensitivity of different aspects of the simulated medicane to the physical parameterizations. Its intensity is mainly influenced by the boundary/surface layer scheme, while its track is mainly influenced by the representation of cumulus convection, and its duration is mainly influenced by microphysical parameterization. The modification of the drag coefficient and the roughness lengths of heat and moisture seems to improve its intensity, track, and duration. The parameterization of shallow convection, with explicitly resolved deep convection, results in a weaker medicane with a shorter lifetime. An optimum combination of physical parameterizations in order to simulate all of the characteristics of the medicane does not seem to exist.
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