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Open AccessArticle

In Silico Analysis of Bioactive Peptides in Invasive Sea Grass Halophila stipulacea

1
Department of Computer Science, Faculty of Science, Dokuz Eylül University, İzmir 35390, Turkey
2
Bioinformatics and High Performance Computing Research Group (BIO-HPC), Computer Engineering Department, Universidad Católica de Murcia (UCAM), 30107 Murcia, Spain
3
Institute of Oncology, Dokuz Eylül University, İzmir 35320, Turkey
4
Department of Chemistry, Faculty of Science, Dokuz Eylül University, İzmir 35390, Turkey
*
Authors to whom correspondence should be addressed.
Academic Editor: Ka-Chun Wong
Cells 2019, 8(6), 557; https://doi.org/10.3390/cells8060557
Received: 4 April 2019 / Revised: 28 May 2019 / Accepted: 30 May 2019 / Published: 7 June 2019
(This article belongs to the Special Issue Bioinformatics and Computational Biology 2019)
Halophila stipulacea is a well-known invasive marine sea grass in the Mediterranean Sea. Having been introduced into the Mediterranean Sea via the Suez Channel, it is considered a Lessepsian migrant. Although, unlike other invasive marine seaweeds, it has not demonstrated serious negative impacts on indigenous species, it does have remarkable invasive properties. The present in-silico study reveals the biotechnological features of H. stipulacea by showing bioactive peptides from its rubisc/o protein. These are features such as antioxidant and hypolipideamic activities, dipeptidyl peptidase-IV and angiotensin converting enzyme inhibitions. The reported data open up new applications for such bioactive peptides in the field of pharmacy, medicine and also the food industry. View Full-Text
Keywords: bioactive peptides; Halophila stipulacea; in silico analysis; DPP-IV; angiotensin converting enzyme inhibitors bioactive peptides; Halophila stipulacea; in silico analysis; DPP-IV; angiotensin converting enzyme inhibitors
MDPI and ACS Style

Kandemir-Cavas, C.; Pérez-Sanchez, H.; Mert-Ozupek, N.; Cavas, L. In Silico Analysis of Bioactive Peptides in Invasive Sea Grass Halophila stipulacea. Cells 2019, 8, 557.

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