Next Article in Journal
Effect of the Statistical Nature of Fiber Strength on the Predictability of Tensile Properties of Polymer Composites Reinforced with Bamboo Fibers: Comparison of Linear- and Power-Law Weibull Models
Next Article in Special Issue
Magnetically-Responsive Hydrogels for Modulation of Chondrogenic Commitment of Human Adipose-Derived Stem Cells
Previous Article in Journal
Phase Behavior and Its Effects on Crystallization in a Poly(trimethylene terephthalate)/Phenoxy Resin Blend
Previous Article in Special Issue
Biomedical Applications of Biodegradable Polyesters
Article Menu

Export Article

Open AccessReview
Polymers 2016, 8(1), 23;

Engineered Polymeric Hydrogels for 3D Tissue Models

Division of Bioengineering, College of Life Sciences and Bioengineering, Incheon National University, 119 Academy-ro, Yeonsu-gu, Incheon 22012, Korea
Author to whom correspondence should be addressed.
Academic Editor: Esmaiel Jabbari
Received: 30 November 2015 / Revised: 4 January 2016 / Accepted: 15 January 2016 / Published: 20 January 2016
(This article belongs to the Special Issue Polymers Applied in Tissue Engineering)
Full-Text   |   PDF [1159 KB, uploaded 20 January 2016]   |  


Polymeric biomaterials are widely used in a wide range of biomedical applications due to their unique properties, such as biocompatibility, multi-tunability and easy fabrication. Specifically, polymeric hydrogel materials are extensively utilized as therapeutic implants and therapeutic vehicles for tissue regeneration and drug delivery systems. Recently, hydrogels have been developed as artificial cellular microenvironments because of the structural and physiological similarity to native extracellular matrices. With recent advances in hydrogel materials, many researchers are creating three-dimensional tissue models using engineered hydrogels and various cell sources, which is a promising platform for tissue regeneration, drug discovery, alternatives to animal models and the study of basic cell biology. In this review, we discuss how polymeric hydrogels are used to create engineered tissue constructs. Specifically, we focus on emerging technologies to generate advanced tissue models that precisely recapitulate complex native tissues in vivo. View Full-Text
Keywords: polymeric hydrogels; engineered tissue models; artificial extracellular matrices; tissue engineering; drug screening; basic cell biology polymeric hydrogels; engineered tissue models; artificial extracellular matrices; tissue engineering; drug screening; basic cell biology

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Park, S.; Park, K.M. Engineered Polymeric Hydrogels for 3D Tissue Models. Polymers 2016, 8, 23.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Polymers EISSN 2073-4360 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top