Next Article in Journal
Electrospun Sesbania Gum-Based Polymeric N-Halamines for Antibacterial Applications
Previous Article in Journal
Effect of Stone-Wales Defect on Mechanical Properties of Gr/epoxy Nanocomposites
Previous Article in Special Issue
Potential of Liquid Extraction Surface Analysis Mass Spectrometry (LESA—MS) for the Characterization of Polymer-Based Materials
Article Menu

Export Article

Open AccessArticle

Sequencing of Side-Chain Liquid Crystalline Copolymers by Matrix-Assisted Laser Desorption/Ionization Tandem Mass Spectrometry

1
Department of Chemistry, The University of Akron, Akron, OH 44325, USA
2
Department of Polymer Science, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200444, China
*
Author to whom correspondence should be addressed.
Polymers 2019, 11(7), 1118; https://doi.org/10.3390/polym11071118
Received: 17 May 2019 / Revised: 10 June 2019 / Accepted: 11 June 2019 / Published: 1 July 2019
(This article belongs to the Special Issue Polymer Mass Spectrometry)
  |  
PDF [3118 KB, uploaded 1 July 2019]
  |  

Abstract

Polyether based side-chain liquid crystalline (SCLC) copolymers with distinct microstructures were prepared using living anionic polymerization techniques. The composition, end groups, purity, and sequence of the resulting copolymers were elucidated by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and tandem mass spectrometry (MS/MS). MALDI-MS analysis confirmed the presence of (CH3)3CO– and –H end groups at the initiating (α) and terminating (ω) chain end, respectively, and allowed determination of the molecular weight distribution and comonomer content of the copolymers. The comonomer positions along the polymer chain were identified by MS/MS, from the fragments formed via C–O and C–C bond cleavages in the polyether backbone. Random and block architectures could readily be distinguished by the contiguous fragment series formed in these reactions. Notably, backbone C–C bond scission was promoted by a radical formed via initial C–O bond cleavage in the mesogenic side chain. This result documents the ability of a properly substituted side chain to induce sequence indicative bond cleavages in the polyether backbone. View Full-Text
Keywords: copolymer sequencing; side-chain liquid crystalline copolymers; charge-induced polyether fragmentation; radical-induced polyether fragmentation; MALDI tandem mass spectrometry copolymer sequencing; side-chain liquid crystalline copolymers; charge-induced polyether fragmentation; radical-induced polyether fragmentation; MALDI tandem mass spectrometry
Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Supplementary material

SciFeed

Share & Cite This Article

MDPI and ACS Style

Snyder, S.R.; Wei, W.; Xiong, H.; Wesdemiotis, C. Sequencing of Side-Chain Liquid Crystalline Copolymers by Matrix-Assisted Laser Desorption/Ionization Tandem Mass Spectrometry. Polymers 2019, 11, 1118.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Polymers EISSN 2073-4360 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top