MicroRNA-Based Diagnosis and Treatment of Metastatic Human Osteosarcoma
Abstract
:1. Introduction
2. Aberrant Expression of miRNA Related to Invasion and Metastasis of Osteosarcoma Cells
3. Circulating miRNA in Blood as a Diagnostic Marker of Osteosarcoma Metastasis
4. Developing Treatment Strategies for Metastatic Osteosarcoma Using Oligonucleotide Drugs
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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miRNA | Expression | Normalization | Technique | Reference |
---|---|---|---|---|
miR-27a | Up | U6 | qRT-PCR | [73] |
miR-195-5p | Up | serum volume | qRT-PCR | [74] |
miR-199a-3p | Up | serum volume | qRT-PCR | [74,75] |
miR-221 | Up | U6 | qRT-PCR | [76,77] |
miR-34b | Down | miR-39 | qRT-PCR | [78] |
miR-95-3p | Down | U6 | qRT-PCR | [79] |
miR-133b | Down | U6 | qRT-PCR | [80] |
miR-195-5p | Down | U6 | qRT-PCR | [81] |
miR-206 | Down | U6 | qRT-PCR | [80] |
miR-223-5p | Down | U6 | qRT-PCR | [82] |
miR-326 | Down | RNU48 | qRT-PCR | [83] |
miR-375 | Down | U6 | qRT-PCR | [84] |
miR-491 | Down | U6 | qRT-PCR | [85] |
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Sasaki, R.; Osaki, M.; Okada, F. MicroRNA-Based Diagnosis and Treatment of Metastatic Human Osteosarcoma. Cancers 2019, 11, 553. https://doi.org/10.3390/cancers11040553
Sasaki R, Osaki M, Okada F. MicroRNA-Based Diagnosis and Treatment of Metastatic Human Osteosarcoma. Cancers. 2019; 11(4):553. https://doi.org/10.3390/cancers11040553
Chicago/Turabian StyleSasaki, Ryo, Mitsuhiko Osaki, and Futoshi Okada. 2019. "MicroRNA-Based Diagnosis and Treatment of Metastatic Human Osteosarcoma" Cancers 11, no. 4: 553. https://doi.org/10.3390/cancers11040553