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Recent Advances in Continuous-Flow Particle Manipulations Using Magnetic Fluids

Department of Mechanical Engineering, Clemson University, Clemson, SC 29634-0921, USA
Micromachines 2019, 10(11), 744; https://doi.org/10.3390/mi10110744
Received: 3 October 2019 / Revised: 28 October 2019 / Accepted: 29 October 2019 / Published: 31 October 2019
(This article belongs to the Special Issue 10th Anniversary of Micromachines)
Magnetic field-induced particle manipulation is simple and economic as compared to other techniques (e.g., electric, acoustic, and optical) for lab-on-a-chip applications. However, traditional magnetic controls require the particles to be manipulated being magnetizable, which renders it necessary to magnetically label particles that are almost exclusively diamagnetic in nature. In the past decade, magnetic fluids including paramagnetic solutions and ferrofluids have been increasingly used in microfluidic devices to implement label-free manipulations of various types of particles (both synthetic and biological). We review herein the recent advances in this field with focus upon the continuous-flow particle manipulations. Specifically, we review the reported studies on the negative magnetophoresis-induced deflection, focusing, enrichment, separation, and medium exchange of diamagnetic particles in the continuous flow of magnetic fluids through microchannels. View Full-Text
Keywords: negative magnetophoresis; paramagnetic solution; ferrofluid; particle deflection; particle focusing; particle enrichment; particle separation; particle medium exchange negative magnetophoresis; paramagnetic solution; ferrofluid; particle deflection; particle focusing; particle enrichment; particle separation; particle medium exchange
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Xuan, X. Recent Advances in Continuous-Flow Particle Manipulations Using Magnetic Fluids. Micromachines 2019, 10, 744.

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