The Reciprocal Interactions between Polyphenols and Gut Microbiota and Effects on Bioaccessibility
by
Tugba Ozdal 1, David A. Sela 2,†
, Jianbo Xiao 3,†, Dilek Boyacioglu 4,†, Fang Chen 5,† and Esra Capanoglu 4,*
Tugba Ozdal 1, David A. Sela 2,†, Jianbo Xiao 3,†, Dilek Boyacioglu 4,†, Fang Chen 5,† and Esra Capanoglu 4,*
1
Department of Food Engineering, Faculty of Engineering and Architecture, Okan Univesity, Tuzla, Istanbul TR-34959, Turkey
2
Department of Food Science, University of Massachusetts Amherst, Amherst, MA 01003, USA
3
Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Taipa, Macau, China
4
Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, Maslak, Istanbul TR-34469, Turkey
5
College of Food Science and Nutritional Engineering, National Engineering Research Centre for Fruits and Vegetables Processing, China Agricultural University, Beijing 100083, China
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Nutrients 2016, 8(2), 78; https://doi.org/10.3390/nu8020078
Received: 8 October 2015 / Accepted: 11 January 2016 / Published: 6 February 2016
(This article belongs to the Special Issue Selected Papers from 2015 International Symposium on Phytochemicals in Medicine and Food)
As of late, polyphenols have increasingly interested the scientific community due to their proposed health benefits. Much of this attention has focused on their bioavailability. Polyphenol–gut microbiota interactions should be considered to understand their biological functions. The dichotomy between the biotransformation of polyphenols into their metabolites by gut microbiota and the modulation of gut microbiota composition by polyphenols contributes to positive health outcomes. Although there are many studies on the in vivo bioavailability of polyphenols, the mutual relationship between polyphenols and gut microbiota is not fully understood. This review focuses on the biotransformation of polyphenols by gut microbiota, modulation of gut microbiota by polyphenols, and the effects of these two-way mutual interactions on polyphenol bioavailability, and ultimately, human health.
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Keywords:
polyphenols; phenolics; flavonoids; gut microbiota; microbial metabolism; bioavailability; health; interactions
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MDPI and ACS Style
Ozdal, T.; Sela, D.A.; Xiao, J.; Boyacioglu, D.; Chen, F.; Capanoglu, E. The Reciprocal Interactions between Polyphenols and Gut Microbiota and Effects on Bioaccessibility. Nutrients 2016, 8, 78.
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