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Open AccessArticle

Consumption of a Diet Rich in Cottonseed Oil (CSO) Lowers Total and LDL Cholesterol in Normo-Cholesterolemic Subjects

Nutrition and Food Sciences, Texas Woman’s University, PO Box 425888, Denton, TX 76204, USA
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Nutrients 2012, 4(7), 602-610; https://doi.org/10.3390/nu4070602
Received: 26 April 2012 / Revised: 29 May 2012 / Accepted: 18 June 2012 / Published: 26 June 2012
Animal data indicates that dietary cottonseed oil (CSO) may lower cholesterol; however, the effects of a CSO-rich diet have not been evaluated in humans. Thirty-eight healthy adults (aged 18–40; 12 males, 26 females) consumed a CSO rich diet (95 g CSO daily) for one week. Anthropometric measurements were obtained, and blood was drawn pre- and post-intervention. Serum lipids (total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), triglyceride (TG), and free fatty acids (FFA)) were assayed. There was no change in weight or waist circumference among participants. There was no change in HDL (Pre: 1.27 ± 0.4 mmol/L; Post: 1.21 ± 0.3 mmol/L) or TG (Pre: 0.91 ± 0.6 mmol/L; Post: 1.06 ± 1.0 mmol/L). Total cholesterol and LDL were reduced (TC Pre: 4.39 ± 0.9 mmol/L; Post: 4.16 ± 0.8 mmol/L; LDL Pre: 2.70 ± 0.8 mmol/L; Post: 2.47 ± 0.6 mmol/L). When data were grouped by sex, total cholesterol was reduced in female participants (Pre: 4.34 ± 0.9 mmol/L; Post: 4.09 ± 0.8 mmol/L). Consumption of a high fat, CSO-rich diet for one week reduced total cholesterol in female participants without reducing HDL. View Full-Text
Keywords: cardiovascular disease; cholesterol; cottonseed oil; lipid profile; triglycerides cardiovascular disease; cholesterol; cottonseed oil; lipid profile; triglycerides
MDPI and ACS Style

Davis, K.E.; Prasad, C.; Imrhan, V. Consumption of a Diet Rich in Cottonseed Oil (CSO) Lowers Total and LDL Cholesterol in Normo-Cholesterolemic Subjects. Nutrients 2012, 4, 602-610. https://doi.org/10.3390/nu4070602

AMA Style

Davis KE, Prasad C, Imrhan V. Consumption of a Diet Rich in Cottonseed Oil (CSO) Lowers Total and LDL Cholesterol in Normo-Cholesterolemic Subjects. Nutrients. 2012; 4(7):602-610. https://doi.org/10.3390/nu4070602

Chicago/Turabian Style

Davis, Kathleen E.; Prasad, Chandan; Imrhan, Victorine. 2012. "Consumption of a Diet Rich in Cottonseed Oil (CSO) Lowers Total and LDL Cholesterol in Normo-Cholesterolemic Subjects" Nutrients 4, no. 7: 602-610. https://doi.org/10.3390/nu4070602

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