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8 January 2026

Approach to Malnutrition and Oral Nutrition Therapy in Adults with IBD: What to Consider

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1
Department of Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic, Cleveland, OH 44195, USA
2
Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA
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This article belongs to the Special Issue Nutritional Management in IBD: From Malnutrition Diagnosis to Targeted Therapy

Abstract

Inflammatory Bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are chronic gastrointestinal conditions that are prone to malnutrition due to poor oral intake, intestinal compromise of nutrient absorption, and increase in metabolic demand. Screening and diagnosing malnutrition in this population is necessary to treat and prevent worsening malnutrition. The use of Oral Nutritional Therapy (ONS) can provide the macronutrients that patients need to maintain their nutrition, however their role in within stages of diseases, active disease, remission, perioperative, and maintenance in relation to other nutritional therapies, such as enteral nutrition or parenteral nutrition, is unclear. This review will highlight the principles of diagnosing malnutrition, the evidence of ONS in disease and remission states, and the role of oral vitamins in the management of IBD.

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