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Open AccessCommunication

Human Milk Fatty Acid Composition of Allergic and Non-Allergic Mothers: The Ulm SPATZ Health Study

1
Pediatric Epidemiology, Department of Pediatrics, Medical Faculty, Leipzig University, 04103 Leipzig, Germany
2
Institute of Epidemiology and Medical Biometry, Ulm University, 89075 Ulm, Germany
3
Danone Nutricia Research, 3584 CT Utrecht, The Netherlands
4
Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands
5
Department of Paediatrics, Medical School, University of Pécs, H-7623 Pécs, Hungary
*
Author to whom correspondence should be addressed.
Nutrients 2020, 12(6), 1740; https://doi.org/10.3390/nu12061740
Received: 8 May 2020 / Revised: 29 May 2020 / Accepted: 7 June 2020 / Published: 10 June 2020
(This article belongs to the Section Nutritional Epidemiology)
The aim of this study was to determine the differences in human milk fatty acid composition in relation to maternal allergy within a large birth cohort study using statistical methods accounting for the correlations that exist in compositional data. We observed marginal differences in human milk fatty acid composition of allergic and non-allergic mothers. However, our results do not support the hypothesis that human milk fatty acid composition is influenced by allergy or that it differs between mothers with or without allergy. Observed differences in our results between transformed and untransformed fatty acid data call for re-evaluation of previous, as well as future, studies using statistical methods appropriate for compositionality of fatty acid data. View Full-Text
Keywords: human milk; fatty acids; maternal allergy human milk; fatty acids; maternal allergy
MDPI and ACS Style

Siziba, L.P.; Lorenz, L.; Stahl, B.; Mank, M.; Marosvölgyi, T.; Decsi, T.; Rothenbacher, D.; Genuneit, J. Human Milk Fatty Acid Composition of Allergic and Non-Allergic Mothers: The Ulm SPATZ Health Study. Nutrients 2020, 12, 1740.

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