Next Article in Journal
Utilizing Dietary Nutrient Ratios in Nutritional Research: Expanding the Concept of Nutrient Ratios to Macronutrients
Previous Article in Journal
The Impact of Ramadan Fasting on the Reduction of PASI Score, in Moderate-To-Severe Psoriatic Patients: A Real-Life Multicenter Study
Article Menu
Issue 2 (February) cover image

Export Article

Open AccessArticle
Nutrients 2019, 11(2), 280; https://doi.org/10.3390/nu11020280

Association of Total and Trimester-Specific Gestational Weight Gain Rate with Early Infancy Weight Status: A Prospective Birth Cohort Study in China

1
Department of Social Medicine, School of Public Health, China Medical University, Shenyang 110122, Liaoning, China
2
Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School, Boston, MA 02215, USA
3
Department of Obstetrics and Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, 119228 Singapore, Singapore
4
Agency for Science, Technology and Research, Singapore Institute for Clinical Sciences, 119228 Singapore, Singapore
5
Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02113, USA
6
Department of Epidemiology and Health Statistics, School of Public Health, China Medical University, Shenyang 110122, Liaoning, China
7
Department of Curriculum and Teaching Research, Research Center of Medical Education, China Medical University, Shenyang 110122, Liaoning, China
*
Author to whom correspondence should be addressed.
Received: 18 December 2018 / Revised: 19 January 2019 / Accepted: 23 January 2019 / Published: 28 January 2019
  |  
PDF [692 KB, uploaded 28 January 2019]
  |     |  

Abstract

Studies to examine the associations of gestational weight gain (GWG) with offspring weight status during infancy are needed, especially among Asian populations. We examined 801 mother–infant pairs from a prospective cohort study in China to assess the associations of total and trimester-specific GWG with early infant weight status. We used linear mixed effects models and linear regression models to examine the longitudinal and time-point associations of GWG rate (kg/week) with infant growth measures (z-scores of body-mass-index (BMIZ), weight-for-age (WFAZ) and length-for-age (LFAZ)) at birth, 1, 3, and 6 months. Greater total GWG rate was associated with higher BMIZ (β:1.34 SD units (95% CI: 0.84, 1.83) per 1 kg/week increase in GWG) and higher WFAZ (β:1.18 SD units (95% CI: 1.01, 2.28)) across the first 6 months of life. GWG rate in the first two trimesters but not in the third trimester was positively associated with infant BMIZ. The association between GWG rate and infant BMIZ was significant at all timepoints and more pronounced in normal weight women and among male infants. In conclusion, greater GWG rate is positively associated with offspring BMIZ in the first 6 months of life, the association is mostly driven by GWG in the first two trimesters. View Full-Text
Keywords: gestation weight gain; trimester-specific; infancy; weight status; body mass index gestation weight gain; trimester-specific; infancy; weight status; body mass index
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Supplementary materials

  • Supplementary File 1:

    PDF-Document (PDF, 215 KB)

  • Externally hosted supplementary file 1
    Doi: 10.6084/m9.figshare.7476446
    Description: Figure S1. Study flow diagram. Table S1. Associations of total and trimester-specific gestational weight gain rate with infant weight-for-length z-score from birth to 6 months using linear mixed effects model Table S2. Associations of total and trimester-specific gestational weight gain rate with infant growth measures from birth to 6 months using linear mixed effects model, further adjusting for infant feeding style, television watching and secondhand smoking exposure at 1 month.
SciFeed

Share & Cite This Article

MDPI and ACS Style

Hu, J.; Aris, I.M.; Oken, E.; Ma, Y.; Ding, N.; Gao, M.; Wei, X.; Wen, D. Association of Total and Trimester-Specific Gestational Weight Gain Rate with Early Infancy Weight Status: A Prospective Birth Cohort Study in China. Nutrients 2019, 11, 280.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top