Vitamin K in Chronic Kidney Disease
AbstractVitamin K is a composite term referring to a group of fat-soluble vitamins that function as a cofactor for the enzyme γ-glutamyl carboxylase (GGCX), which activates a number of vitamin K-dependent proteins (VKDPs) involved in haemostasis and vascular and bone health. Accumulating evidence demonstrates that chronic kidney disease (CKD) patients suffer from subclinical vitamin K deficiency, suggesting that this represents a population at risk for the biological consequences of poor vitamin K status. This deficiency might be caused by exhaustion of vitamin K due to its high requirements by vitamin K-dependent proteins to inhibit calcification. View Full-Text
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Cozzolino, M.; Mangano, M.; Galassi, A.; Ciceri, P.; Messa, P.; Nigwekar, S. Vitamin K in Chronic Kidney Disease. Nutrients 2019, 11, 168.
Cozzolino M, Mangano M, Galassi A, Ciceri P, Messa P, Nigwekar S. Vitamin K in Chronic Kidney Disease. Nutrients. 2019; 11(1):168.Chicago/Turabian Style
Cozzolino, Mario; Mangano, Michela; Galassi, Andrea; Ciceri, Paola; Messa, Piergiorgio; Nigwekar, Sagar. 2019. "Vitamin K in Chronic Kidney Disease." Nutrients 11, no. 1: 168.
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