Harnessing Artificial Intelligence and Digital Technologies for Sustainable Healthcare Delivery in Saudi Arabia: A Comprehensive Review, Issues, and Future Perspectives
Abstract
1. Introduction
- The SLR demonstrates the wide range of artificial intelligence (AI) and digital innovations deployed in Saudi Arabia’s medical industry, such as blockchain, cloud computing, telemedicine, mobile health apps, electronic health records (EHRs), machine learning, and the Internet of Things. It has been demonstrated that these innovations improve patient care, diagnosis, and medical treatment.
- The review emphasizes how digital technology and artificial intelligence (AI) increase patient interaction, facilitate personalized treatment, and facilitate administrative procedures while enhancing diagnostic accuracy.
- The report lists several significant challenges for employing AI and digital technologies, such as concerns about data security and privacy, high implementation costs, reluctance to change, a lack of expertise among medical personnel, interoperability problems, and difficulties with regulations and compliance.
- The review reveals that enhanced workforce digital literacy and strategic public–private partnerships are pivotal to achieving equitable and sustainable AI-driven healthcare transformation in Saudi Arabia.
- The SLR offers practical suggestions for further study, including improving natural language processing (NLP) tailored to Arabic, combining edge computing and 5G, and creating AI-powered mental health systems to meet regional healthcare needs.
2. Evolution of Artificial Intelligence (AI) Paradigms in Healthcare
3. Materials and Methods
3.1. Research Questions
3.2. Search Strategy
3.3. Article Selection Criteria
3.4. The Screening Process and Results
3.5. Quality Assessment (QA)
4. Data Extraction and Synthesis
4.1. Source Distribution of Selected Articles
4.2. Yearly Wisely Distributions of the Selected Articles
5. Review Findings and Discussions
5.1. What Are AI and Digital Technologies That Have Been Implemented in Saudi Arabia’s Healthcare System? (RQ1)
5.1.1. Telemedicine
5.1.2. EHRs
5.1.3. Mobile Health Applications and Wearable Devices
5.1.4. Data Analytics and Machine Learning
5.1.5. IoT
5.1.6. Blockchain Technology
5.1.7. Online Platform
5.1.8. Encryption Technique
5.1.9. Cloud Computing
5.2. How Do AI and Digital Technologies Contribute to Improving the Efficiency of Human Health Outcomes in Saudi Arabia? (RQ2)
5.2.1. Enhanced Diagnosis and Treatment
5.2.2. Telemedicine Expansion
5.2.3. Predictive Analytics for Public Health
5.2.4. Streamlined Administrative Processes
5.2.5. Enhanced Patient Engagement
5.2.6. Medical Research and Training
5.2.7. Smart Hospitals
5.2.8. Support for Vision 2030 Goals
5.3. How Do AI and Digital Technologies Contribute to the Sustainability of Healthcare Systems in Saudi Arabia in Terms of Cost-Efficiency, Environmental Responsibility, and Long-Term Service Delivery? (RQ3)
5.4. What Strategies and Policies Are Being Implemented in Saudi Arabia to Promote the Sustainable Integration of AI and Digital Technologies in Healthcare? (RQ4)
5.5. What Are the Major Challenges and Barriers Faced in Adopting and Integrating AI and Digital Technologies into the Saudi Arabian Healthcare Sector? (RQ5)
5.5.1. Data Privacy and Security
5.5.2. Cost of Implementation
5.5.3. Resistance to Change
5.5.4. Interoperability Issues
5.5.5. Regulatory and Compliance Challenges
5.5.6. Equity in Access
5.5.7. Digital Divide Among Healthcare Professionals
5.5.8. Lack of Digital Skills Among Healthcare Professionals
5.5.9. Technological and Infrastructural Constraints
5.5.10. Ethical, Fairness, and Explainability Considerations in AI Deployment
6. Emerging Trends and Future Avenues
6.1. Big Data and Analytics
6.2. AI-Powered Chatbots to Improve Patient Care
6.3. Mental Health and Wellness Platforms
6.4. Integration of 5G and Edge Computing for Real-Time Healthcare Solutions
6.5. Sustainability and Green Healthcare Technology Initiatives
6.6. Integration of NLP for Arabic Healthcare Applications
6.7. Expansion of AI-Driven Diagnostics
6.8. Ethical AI Development and Regulations
6.9. Future-Ready Healthcare Workforce Development
7. Limitations Related to Study Types
8. Conclusions
Supplementary Materials
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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| Inclusion Criteria (ICC) | |
| ICC1 | Studies that focused on the application of or suggested relevant AI and digital technologies in healthcare environments in Saudi Arabia. |
| ICC2 | Peer-reviewed papers and book chapters were included to maintain the quality. |
| ICC3 | The application or deployment of AI and digital technology must focus on the healthcare domain. |
| ICC4 | Only the primary study is considered in this study. |
| ICC5 | Only publications in the English language were included. |
| ICC6 | Papers published from 2020 to 2025. |
| ICC7 | The study that focused on the application of artificial intelligence techniques within the healthcare domain, specifically related to clinical diagnosis, patient management, clinical decision support, or drug discovery. |
| Exclusion Criteria (ECC) | |
| ECC1 | Studies that have no bearing on AI and digital technologies in healthcare environments dwelt on the Saudi Arabian healthcare system. |
| ECC2 | Non-published works (journal articles, conference papers, and book chapters) to enhance the quality of the selected papers. |
| ECC3 | The application or deployment of AI and digital technology that did not focus on the healthcare domain |
| ECC4 | Non-recent publications, duplicated articles, and other language publications. |
| ECC5 | Non-primary research papers. |
| ECC6 | Papers produced before the year 2020. |
| ECC7 | The study that only focused primarily on public health surveillance, population-level epidemiology, or health policy analysis without a direct clinical or patient-level AI application. |
| Source | Initial Query | Duplicate Removal | Title and Abstract | Full Text Reading | ICC/ECC | Final Selection |
|---|---|---|---|---|---|---|
| PubMed | 201 | 115 | 50 | 39 | 20 | 05 |
| MDPI | 199 | 119 | 60 | 37 | 17 | 03 |
| Science Direct | 129 | 117 | 49 | 32 | 06 | 02 |
| Springer | 163 | 111 | 51 | 35 | 09 | 03 |
| EBSCO | 20 | 15 | 07 | 05 | 01 | 01 |
| Google Scholar | 151 | 112 | 56 | 16 | 13 | 07 |
| Total Qty | 863 | 589 | 274 | 164 | 66 | 21 |
| S/N | QA Criteria |
|---|---|
| QA1 | Clarity of research objectives. |
| QA2 | Transparency of methodology. |
| QA3 | Relevance of findings to the research questions. |
| QA4 | Depth of analysis provided. |
| QA5 | Detailed specification of AI or Digital Tech used in the selected article. |
| QA1 | QA2 | QA3 | QA4 | QA5 | Total Score | |
|---|---|---|---|---|---|---|
| P-1 | ✓ | ✓ | ✓ | ✓ | ✓ | 5 |
| P-2 | ✓ | ✓ | ✓ | ✓ | ✓ | 5 |
| P-3 | ✓ | ✓ | ✓ | ✓ | ✓ | 5 |
| P-4 | ✓ | × | ✓ | ✓ | ✓ | 4 |
| P-5 | ✓ | ✓ | ✓ | × | ✓ | 4 |
| P-6 | ✓ | × | ✓ | ✓ | ✓ | 4 |
| P-7 | ✓ | ✓ | ✓ | ✓ | ✓ | 5 |
| P-8 | ✓ | ✓ | ✓ | ✓ | ✓ | 5 |
| P-9 | ✓ | ✓ | ✓ | ✓ | ✓ | 5 |
| P-10 | ✓ | ✓ | ✓ | ✓ | ✓ | 5 |
| P-11 | ✓ | ✓ | ✓ | ✓ | ✓ | 5 |
| P-12 | ✓ | ✓ | ✓ | ✓ | ✓ | 5 |
| P-13 | ✓ | ✓ | ✓ | ✓ | ✓ | 5 |
| P-14 | ✓ | ✓ | × | ✓ | ✓ | 4 |
| P-15 | ✓ | ✓ | ✓ | ✓ | × | 4 |
| P-16 | ✓ | ✓ | ✓ | ✓ | ✓ | 5 |
| P-17 | ✓ | × | ✓ | ✓ | ✓ | 4 |
| P-18 | ✓ | ✓ | ✓ | ✓ | × | 4 |
| P-19 | ✓ | ✓ | ✓ | ✓ | ✓ | 5 |
| P-20 | ✓ | ✓ | ✓ | ✓ | ✓ | 5 |
| P-21 | ✓ | ✓ | ✓ | ✓ | ✓ | 5 |
| S/N | Classification | Explanation |
|---|---|---|
| 1 | Paper ID | A distinct code is assigned to every paper |
| 2 | References | Author(s) details and publication year |
| 3 | Objective | The purpose of the study |
| 4 | AI and digital technology applications | AI and digital technologies are integrated with the Saudi healthcare sector. |
| 5 | Strategies and policies | Strategies and policies implementation to promote sustainable integration |
| 6 | Findings | Findings obtained from each of the selected primary studies |
| 7 | Barriers and challenges | Barriers and challenges in the deployment of AI and digital technologies in Saudi healthcare |
| 8 | Source | The database is used to retrieve papers |
| Paper-Id | Authors | Objectives | AI and Digital Technologies Applications | Strategies and Policies Implementation to Promote Sustainable Integration | Findings | Challenges and Barriers in Adopting ai and Digital Tech | Source |
|---|---|---|---|---|---|---|---|
| P-1 | [21] | Assess AI in Riyadh healthcare, identify Vision 2030 opportunities, and examine integration challenges. | AI and machine learning | Staff development and capacity building initiatives, public-private partnership program | 60% male, 40% female; 47% MD/PhD; 65% low AI adoption; 53% see AI’s role in Vision 2030. | Privacy/security issues, Lack of digital skills among healthcare professionals. | Google scholars |
| P-2 | [22] | Examine AI potential in Saudi healthcare, and explore drawbacks and role in national health transformation. | Telemedicine, mobile health apps, electronic health records, and AI-powered COVID-19 detection | Saudi Data and Artificial Intelligence Authority (SDAIA), National Healthcare Command and Control Center (NHCCC). | AI shows success in diagnostic radiology, personalized healthcare, and COVID-19 management. Saudi Arabia launched 19 health apps/platforms, established SDAIA and NHCC | Lack of institutional resources, inadequate healthcare worker training, need for better infrastructure. | Google scholars |
| P-3 | [11] | Examine health technology’s role in Saudi healthcare modernization aligned with Vision 2030 | Telemedicine, EHR, mobile health apps, AI diagnostics, VR training, e-learning platforms | Healthcare professional training and capacity building initiatives | Technology improving healthcare access, enabling personalized care, enhancing training, streamlining processes | Infrastructure limitations, workforce training needs, data security risks, AI bias concerns | EBSCO |
| P-4 | [23] | Assess Saudi healthcare providers’ perceptions and concerns about AI in healthcare facilities. | Mobile health applications, machine learning, deep learning | Integration of the AI course into medical training. Collaboration with other medical schools with engineering and computer science faculties. | 55.2% good AI knowledge, 73.3% fear job replacement, 84.9% support AI in medical curricula | Healthcare providers’ concerns about job displacement, and the need for better AI education integration. | PubMed |
| P-5 | [24] | Describe how Saudi Arabia has employed digital technology in the areas of risk communication, education, telecommunication, public health, and healthcare services during the COVID-19 pandemic. | Mobile Health Application | Public private partnership collaboration. | About 19 apps and platforms that support public health initiatives and offer medical services were created and released by Saudi Arabia’s governmental and commercial sectors. | Failure to evaluate the listed apps and user experience. | PubMed |
| P-6 | [25] | Investigate success indicators for cloud computing adoption in Saudi healthcare. | Cloud computing | SDAIA | Attitudes towards technology, data security, compliance, and reliability are key to cloud adoption. | Low adoption rate due to concerns over data privacy, control, and the need for policy formation. | Science Direct |
| P-7 | [26] | Investigate AI utilization in healthcare decision-making by caregivers in Saudi Arabia. | AI algorithms in decision-making, diagnostics, and personalized medicine. | Targeted intervention and training program among caregiver, Collaboration. | 75% of caregivers use AI in decision-making, with significant use among nurses. AI’s adoption varies by demographic factors. | Challenges in AI adoption due to demographic variations and the need for targeted interventions to maximize AI benefits. | PubMed |
| P-8 | [10] | Assess Vision 2030’s impact on healthcare reforms in Saudi Arabia. | Telemedicine, EHRs, and data analytics. | Private public partnership, Healthcare professional training | Vision 2030 enhances preventive care, public health education, and patient-centered approaches. | Cultural resistance to preventive care. Balancing public-private roles. Workforce and legislative gaps. Limited digital infrastructure. | Google scholar |
| P-9 | [27] | To design and test an IoT and big data–based system for hypertension prediction and detection in Saudi Arabia to improve early chronic illness diagnosis and support Vision 2030 healthcare goals. | IoT and Big Data driven ML system for chronic disease (hypertension) prediction/monitoring in Saudi Arabia | Custom-made smart wristbands, custom-made smart clothing, and custom-made smart homes | Age and diabetes are the most significant determinants of hypertension. The SVM surpassed C4.5. The framework illustrates the potential of IoT and big data analytics for the early diagnosis of chronic diseases in accordance with Vision 2030 of Saudi Arabia. | Limited sample size and brief training time.
| PubMed |
| P-10 | [28] | Evaluate knowledge, attitudes, and practices of Saudi healthcare staff on technology use in patient management. | EHRs, telemedicine, and integrated healthcare systems. | Elaborate training interventions for each healthcare role, approaches to managing resistance to change, and information on protection of data. | Positive attitudes toward technology but gaps in training, knowledge, and integration hinder effective use. | Resistance to change, inadequate training, data privacy concerns, and varying proficiency among staff. | Google scholars |
| P-11 | [29] | To explore the perspective of physicians on the current scope and content of non-communicable disease (NCD) management at primary healthcare centers (PHCs) in Saudi Arabia | EHRs | Collaboration between medical professionals and nutritionists, Medical professional training on the use of EHRs. | Significant gaps include the absence of a patient portal, limited access for patients to their health data, and challenges in interconnectivity between healthcare sectors. | Fragmented digital tools require physicians to use multiple platforms, increasing their workload. | Springer |
| P-12 | [30] | To compare Random Forest machine learning algorithm and Logistic Regression algorithm towards the prediction of diabetes | Early prediction of Type 2 Diabetes | Deployment of machine learning technique for Diabetics prediction. | Random Forest far surpassed Logistic Regression on all criteria; AUROC 0.944 compared to 0.708. Exhibits the advantages of machine learning over conventional statistics in identifying diabetes risk. |
| PubMed |
| P-13 | [9] | To define the career pathway for eHealth professions in the Middle East and identify challenges in aligning academic curricula with industry needs. | EHRS, Telemedicine, AI | Healthcare workforce development, private public partner. | Career pathways for eHealth professionals were defined, but challenges exist in hybrid skill requirements, curriculum standardization, and local training programs. | A mismatch between academic training and industry needs, a lack of standardized curricula, and limited local training opportunities. | MDPI |
| P-14 | [31] | To explore digital transformation in the pharmacy sector, focusing on AI, blockchain, and online platforms. | AI, blockchain, online platform. | Collaborative effort among healthcare professionals. | Digital transformation is reshaping pharmacy services, with a projected market growth. | Regulatory challenges in ensuring safety and quality standards. | Springer |
| P-15 | [32] | To examine public perceptions around the use of six Saudi mHealth apps used during COVID-19 using Twitter | M-Health apps, Machine learning (NLP) | Adoption of social media platform (Twitter) for official communication during the pandemics | Most conversations were neutral, reflecting public inquiries and information-sharing | Limited digital literacy and familiarity with mHealth apps and Overlapping app functionalities led to user confusion. | MDPI |
| P-16 | [33] | Develop a privacy-preserving and DL-based diagnostic methodology for the Internet of Medical Things (IoMT) | Cloud computing and IoT adoption in healthcare. | ElGamal public key cryptosystem with Rat Swarm Optimizer (EIG-RSO) employed for secure data transmission. | Efficient in decreasing computation overhead and improving diagnostic accuracy | Significant computational demands for implementing deep learning models on Internet of Medical Things devices with constrained resources | Springer |
| P-17 | [34] | To develop an efficient encryption algorithm for safeguarding patient data in cloud-based healthcare systems | Private key encryption technique | Lionized remora optimization-based serpent (LRO-S) employed for sensitive data encryption. | The proposed framework significantly reduced encryption and decryption times compared to existing methods. | Complexity in implementing hybrid algorithms across diverse healthcare systems | MDPI |
| P-18 | [35] | To develop an Artificial Intelligence-enabled Decision Support System for Cardiovascular Disease (CVD) detection and classification in smart city e-healthcare environments | Cloud computing for data storage and analysis | Artificial Intelligence Enabled Decision Support System for CVD Disease Detection and Classification (AIDSS-CDDC) for effectual detection of CVD | The proposed approach has shown exceptional performance accuracy (reaching 98.35%) and efficiency in identifying and categorizing cardiovascular disease (CVD). | Improving the precision of non-invasive diagnostic methods while reconciling data privacy issues with efficient data application. | Google Scholar |
| P-19 | [36] | To enhance privacy and security in Electronic Health Records (EHR) utilizing AI and multi-agent systems integrated with Distributed Ledger Technology (DLT) | AI and Blockchain technology ensures decentralization, immutability, and secure handling of EHR data. | Data privacy | The incorporation of AI-driven intelligent agents and blockchain technology substantially enhances the security and confidentiality of electronic health record systems. | Challenges with integrating and scaling the incorporation of artificial intelligence, multi-agent systems, and blockchain within existing electronic health record infrastructure | PubMed |
| P-20 | [37] | To evaluate the development and significance of telehealth and e-health as depicted in various informatics. mobile applications during the COVID-19 pandemic in Saudi Arabia | Telemedicine and mobile health applications. | Telemedicine is the most effective strategy for the COVID-19 pandemic. Data privacy and informed consent. | Findings show that telemedicine remains the most effective solution to pandemics like COVID-19. | The overall awareness and interest in telemedicine after the end of the COVID-19 pandemic remains a challenge. | Science Direct |
| P-21 | [38] | To develop AI-powered healthcare framework that integrates Generative Artificial Intelligence (GAI), Reinforcement Learning from Human Feedback (RLHF), and the Analytic Network Process (ANP). RLHF enables AI models to learn and adapt based on real-time user feedback | GAI, RLHF, and ANP | Hybrid Generative-AI framework: Reinforcement Learning from Human Feedback (RLHF) + Analytic Network Process (ANP) based on a pre-trained language model and a reward model | RLHF + ANP algorithm attains 98.8% accuracy with significantly reduced latency (0.05 ms) and overhead compared to CNN, LSTM, RNN, and vanilla GAI; delivers quicker, more personalized, customer-focused services associated with Vision 2030. | Noise present in raw data; requirement for real-time adaptability and security; limited availability of previous Saudi datasets; sophistication involved in integrating RLHF with ANP | Science Direct |
| S/N | AI and Digital Tech | References | Frequency | Evidence They Provide |
|---|---|---|---|---|
| 1 | Telemedicine | P-2, P-3, P-8, P-10, P-13, P-20 | 6 | Implementation |
| 2 | Electronic Health Records (EHRs) | P-2, P-3, P-8, P-10, P-11, P-13, P-19 | 7 | Implementation |
| 3 | Mobile health applications and wearable devices | P-2, P-3, P-5, P-9, P-15, P-20 | 6 | Implementation |
| 4 | Data analytics and Machine Learning | P-1, P-4, P-7, P-12, P-18, P-21 | 6 | Model performance/Implementation |
| 5 | Internet of Things (IoT) | P-9, P-16, P-18 | 3 | Model performance |
| 6 | Blockchain technology | P-14, P-19 | 2 | Implementation |
| 7 | Online platforms | P-5, P-14, P-20 | 3 | Implementation |
| 8 | Cloud computing | P-6, P-16, P-18 | 3 | Implementation |
| 9 | Encryption algorithms | P-17, P-19 | 2 | Model performance |
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Share and Cite
Alsehani, F.N. Harnessing Artificial Intelligence and Digital Technologies for Sustainable Healthcare Delivery in Saudi Arabia: A Comprehensive Review, Issues, and Future Perspectives. Sustainability 2026, 18, 1461. https://doi.org/10.3390/su18031461
Alsehani FN. Harnessing Artificial Intelligence and Digital Technologies for Sustainable Healthcare Delivery in Saudi Arabia: A Comprehensive Review, Issues, and Future Perspectives. Sustainability. 2026; 18(3):1461. https://doi.org/10.3390/su18031461
Chicago/Turabian StyleAlsehani, Fayez Nahedh. 2026. "Harnessing Artificial Intelligence and Digital Technologies for Sustainable Healthcare Delivery in Saudi Arabia: A Comprehensive Review, Issues, and Future Perspectives" Sustainability 18, no. 3: 1461. https://doi.org/10.3390/su18031461
APA StyleAlsehani, F. N. (2026). Harnessing Artificial Intelligence and Digital Technologies for Sustainable Healthcare Delivery in Saudi Arabia: A Comprehensive Review, Issues, and Future Perspectives. Sustainability, 18(3), 1461. https://doi.org/10.3390/su18031461

