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Case Report

Acute Respiratory Failure as Primary Manifestation of Antineutrophil Cytoplasmic Antibodies-Associated Vasculitis

1
Respiratory Intensive Care Unit, Aristotle University of Thessaloniki, G.H. “G. Papanikolaou”, Thessaloniki, Greece
2
Department of Pneumonology, Aristotle University of Thessaloniki, G.H. “G. Papanikolaou”, Thessaloniki, Greence
*
Author to whom correspondence should be addressed.
Clin. Pract. 2014, 4(2), 653; https://doi.org/10.4081/cp.2014.653
Submission received: 11 May 2014 / Revised: 11 May 2014 / Accepted: 12 June 2014 / Published: 4 July 2014

Abstract

The systemic vasculitides are multifocal diseases characterized by the presence of blood vessel inflammation in multiple organ systems. Their clinical presentation is variable extending from self-limited illness to critical complications including diffuse alveolar hemorrhage and glomerulonephritis. Alveolar hemorrhage is a lifethreatening manifestation of pulmonary vasculitis that can rapidly progress into acute respiratory failure requiring ventilatory support. We present the case of a 74-year-old patient admitted to the Intensive Care Unit with severe hypoxic respiratory failure and diffuse alveolar infiltrates in chest imaging that was later diagnosed as antineutrophil cytoplasmic antibodies-associated vasculitis. The report highlights the importance of differentiate between alveolar hemorrhage and acute respiratory distress syndrome of other etiology because alveolar hemorrhage is reversible with prompt initiation of treatment.
Keywords: respiratory failure; vasculitis; antineutrophil cytoplasmic antibodies; alveolar infiltrates respiratory failure; vasculitis; antineutrophil cytoplasmic antibodies; alveolar infiltrates

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MDPI and ACS Style

Sourla, E.; Bagalas, V.; Tsioulis, H.; Paspala, A.; Akritidou, S.; Pataka, A.; Fekete, K.; Kioumis, I.P.; Stanopoulos, I.; Pitsiou, G. Acute Respiratory Failure as Primary Manifestation of Antineutrophil Cytoplasmic Antibodies-Associated Vasculitis. Clin. Pract. 2014, 4, 653. https://doi.org/10.4081/cp.2014.653

AMA Style

Sourla E, Bagalas V, Tsioulis H, Paspala A, Akritidou S, Pataka A, Fekete K, Kioumis IP, Stanopoulos I, Pitsiou G. Acute Respiratory Failure as Primary Manifestation of Antineutrophil Cytoplasmic Antibodies-Associated Vasculitis. Clinics and Practice. 2014; 4(2):653. https://doi.org/10.4081/cp.2014.653

Chicago/Turabian Style

Sourla, Evdokia, Vasilis Bagalas, Helias Tsioulis, Asimina Paspala, Sofia Akritidou, Athanasia Pataka, Katalin Fekete, Ioannis P. Kioumis, Ioannis Stanopoulos, and Georgia Pitsiou. 2014. "Acute Respiratory Failure as Primary Manifestation of Antineutrophil Cytoplasmic Antibodies-Associated Vasculitis" Clinics and Practice 4, no. 2: 653. https://doi.org/10.4081/cp.2014.653

APA Style

Sourla, E., Bagalas, V., Tsioulis, H., Paspala, A., Akritidou, S., Pataka, A., Fekete, K., Kioumis, I. P., Stanopoulos, I., & Pitsiou, G. (2014). Acute Respiratory Failure as Primary Manifestation of Antineutrophil Cytoplasmic Antibodies-Associated Vasculitis. Clinics and Practice, 4(2), 653. https://doi.org/10.4081/cp.2014.653

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