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Clinics and Practice, Volume 11, Issue 4

December 2021 - 26 articles

Cover Story: Lupus nephritis (LN), is common in patients with systemic lupus erythrocytosis (SLE) with 60% of cases presenting with early LN at the time of diagnosis. LN manifests mainly with the full-house immunofluorescence and various electron-dense deposits in the mesangium, subepithelial or subendothelial regions. Traditionally, proteinuria and hematuria in these patients was thought to be due to the immune complex deposition. However, in a subset of nephrotic lupus patients, there is no subepithelial/subendothelial deposits and there is an extensive podocyte effacement, leading to nephrotic-range proteinuria, and is termed lupus podocytopathy (LP). This could highlight the role of the circulating cytokines, mainly interleukin 13, in the pathophysiology of LP and the renal histology for accurate diagnosis and proper management of NS in patients with SLE. View this paper.
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Articles (26)

  • Article
  • Open Access
3,409 Views
7 Pages

Clinical and Epidemiological Characteristics of COVID-19 Patients with SARS-CoV-2 Re-Detected on PCR Test after Discharge from Isolation

  • Abdullah J. Alsahafi,
  • Manal M. Al Daajani,
  • Ahmed A. Osman,
  • Abdulhamed L. Moawwad,
  • Abdullah M. Algarni,
  • Ibrahim M. Asiri,
  • Wadea O. Nofal and
  • Rayan M. Alselami

18 December 2021

There have been multiple reports of patients with coronavirus disease (COVID-19) testing positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after discharge; however, information on the characteristics of such cases is limited....

  • Article
  • Open Access
5 Citations
3,254 Views
7 Pages

Tracheotomy Outcomes in 71 COVID-19 Patients: A Multi-Centric Study in Saudi Arabia

  • Dakheelallah Almutairi,
  • Raneem Alqahtani,
  • Arwa Alghamdi,
  • Dina Binammar,
  • Suzan Alzaidi,
  • Abdullah Ghafori and
  • Hassan Alsharif

15 December 2021

Since its outbreak in late 2019, the COVID-19 pandemic has seen a sharp rise in the demand for oxygen and ventilation facilities due to the associated extensive damage that it causes to the lungs. This study is considered the first and largest study...

  • Case Report
  • Open Access
4 Citations
5,216 Views
5 Pages

Zinner Syndrome—A Rare Cause of Recurrent Epididymitis and Infertility

  • Magdalena Ostrowska,
  • Magdalena Grześk,
  • Szymon Kaczyński,
  • Dominika Skwara,
  • Kacper Kulik,
  • Filip Kowalski,
  • Adam Ostrowski and
  • Tomasz Drewa

9 December 2021

Zinner syndrome (ZS) is a rare disorder that affects only men. It is characterized by a triad of abnormalities, including unilateral renal agenesis, ipsilateral seminal vesicle cysts, and atresia of the ejaculatory tract. Unfortunately, there is no c...

  • Article
  • Open Access
3,241 Views
9 Pages

Clinical Characteristics, Treatment, and Short-Term Outcome in Patients with Heart Failure and Cancer

  • Jędrzej Piotrowski,
  • Małgorzata Timler,
  • Remigiusz Kozłowski,
  • Arkadiusz Stasiak,
  • Joanna Stasiak,
  • Andrzej Bissinger,
  • Dariusz Timler,
  • Wojciech Timler,
  • Michał Marczak and
  • Roman Załuska
  • + 1 author

6 December 2021

(1) Our study aimed to look at the clinical characteristics, treatment and short-term outcomes of patients hospitalized due to heart failure with coexisting cancer. (2) Methods: Seventy one cancer (Ca) patients and a randomly selected 70 patients wit...

  • Article
  • Open Access
9 Citations
4,557 Views
14 Pages

2 December 2021

Coordination of care for patients with neuro-ophthalmic disorders can be very challenging in the community emergency department (ED) setting. Unlike university- or tertiary hospital-based EDs, the general ophthalmologist is often not as familiar with...

  • Review
  • Open Access
5 Citations
5,311 Views
13 Pages

26 November 2021

Modern advances in molecular medicine have led to the reframing of osteoarthritis as a metabolically active, inflammatory disorder with local and systemic contributing factors. According to the ‘inflammatory theory’ of osteoarthritis, imm...

  • Case Report
  • Open Access
4 Citations
4,531 Views
5 Pages

Hormonal Contraception and Massive Pulmonary Embolism in a COVID-19 Ambulatory Patient: A Case Report

  • Laura Valenzuela-Vallejo,
  • David Corredor-Orlandelli,
  • Sergio Alzate-Ricaurte,
  • Valentina Hernández-Santamaría,
  • Juan Felipe Aguirre-Ruiz and
  • Adwar Peña-Peña

26 November 2021

Coronavirus 19 disease (COVID-19) presents a highly variable clinical presentation and course, ranging from asymptomatic patients to rapidly progressive, fatal pneumonia. The known heterogeneous outcomes can affect both previously healthy patients an...

  • Review
  • Open Access
30 Citations
10,284 Views
23 Pages

New Aspects of Sarcomas of Uterine Corpus—A Brief Narrative Review

  • Stoyan Kostov,
  • Yavor Kornovski,
  • Vesela Ivanova,
  • Deyan Dzhenkov,
  • Dimitar Metodiev,
  • Rafał Watrowski,
  • Yonka Ivanova,
  • Stanislav Slavchev,
  • Dimitar Mitev and
  • Angel Yordanov

22 November 2021

Sarcomas of the uterine corpus are rare malignant neoplasms, which are further classified into mesenchymal tumors, and mixed (epithelial plus mesenchymal) tumors. The main issues concerning these neoplasms are the small number of clinical trials, ins...

  • Case Report
  • Open Access
2 Citations
4,755 Views
8 Pages

Congenital Adrenal Hyperplasia: Diagnostic Pitfalls in Prolonged Neonatal Jaundice

  • Nur Athirah Rosli,
  • Md Yasin Mazapuspavina and
  • Noor Shafina Mohd Nor

17 November 2021

Congenital Adrenal Hyperplasia (CAH) is a genetic disorder that leads to cortisol deficiency. However, prolonged neonatal jaundice is a rare presentation of CAH. The pathophysiology of hyperbilirubinemia in CAH is still ill-defined. Plausible causes...

  • Article
  • Open Access
9 Citations
3,181 Views
10 Pages

Quality of Life among Pediatric Neurocognitive, Speech, and Psychomotor Rehabilitation Professionals during the COVID-19 Pandemic: A Longitudinal Study on an Italian Sample

  • Vincenza Cofini,
  • Valeria Bianchini,
  • Mario Muselli,
  • Danila Budroni,
  • Loreta Tobia,
  • Giovanna Letizia Calò,
  • Leila Fabiani and
  • Stefano Necozione

15 November 2021

Objective: The aim was to estimate the perceived quality of life and its relationship with sociodemographic and professional factors, perception of susceptibility to COVID-19, and stress. Design: It was a longitudinal study. Subjects: Professionals,...

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Clin. Pract. - ISSN 2039-7283