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Brief Report

Hyperlipidemia and Obesity’s Role in Immune Dysregulation Underlying the Severity of COVID-19 Infection

1
College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA 91766, USA
2
Department of Emergency Medicine, St. Barnabas Hospital Health System, Bronx, NY 10457, USA
3
Department of Basic Medical Sciences, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, 309 E Second Street, Pomona, CA 91766, USA
*
Author to whom correspondence should be addressed.
Clin. Pract. 2021, 11(4), 694-707; https://doi.org/10.3390/clinpract11040085
Received: 3 August 2021 / Revised: 17 September 2021 / Accepted: 17 September 2021 / Published: 22 September 2021
Obesity and hyperlipidemia are known to be risk factors for various pathological disorders, including various forms of infectious respiratory disease, including the current Coronavirus outbreak termed Coronavirus Disease 19 (COVID-19). This review studies the effects of hyperlipidemia and obesity on enhancing the inflammatory response seen in COVID-19 and potential therapeutic pathways related to these processes. In order to better understand the underlying processes of cytokine and chemokine-induced inflammation, we must further investigate the immunomodulatory effects of agents such as Vitamin D and the reduced form of glutathione as adjunctive therapies for COVID-19 disease. View Full-Text
Keywords: hyperlipidemia; SARS-CoV-2; COVID-19 hyperlipidemia; SARS-CoV-2; COVID-19
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MDPI and ACS Style

Khatchadourian, C.; Sisliyan, C.; Nguyen, K.; Poladian, N.; Tian, Q.; Tamjidi, F.; Luong, B.; Singh, M.; Robison, J.; Venketaraman, V. Hyperlipidemia and Obesity’s Role in Immune Dysregulation Underlying the Severity of COVID-19 Infection. Clin. Pract. 2021, 11, 694-707. https://doi.org/10.3390/clinpract11040085

AMA Style

Khatchadourian C, Sisliyan C, Nguyen K, Poladian N, Tian Q, Tamjidi F, Luong B, Singh M, Robison J, Venketaraman V. Hyperlipidemia and Obesity’s Role in Immune Dysregulation Underlying the Severity of COVID-19 Infection. Clinics and Practice. 2021; 11(4):694-707. https://doi.org/10.3390/clinpract11040085

Chicago/Turabian Style

Khatchadourian, Christopher, Christina Sisliyan, Kevin Nguyen, Nicole Poladian, Qi Tian, Faraaz Tamjidi, Bao Luong, Manpreet Singh, Jeremiah Robison, and Vishwanath Venketaraman. 2021. "Hyperlipidemia and Obesity’s Role in Immune Dysregulation Underlying the Severity of COVID-19 Infection" Clinics and Practice 11, no. 4: 694-707. https://doi.org/10.3390/clinpract11040085

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